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- W2412724246 abstract "Based on repeated interval analyses, radiotherapy and cytostatic drug therapy were stepwise intensified and combined in 264 patients diagnosed between 1976 and 1981 as having histopathologically low-malignant centroblastic-centrocytic (cb/cc; n = 106), centrocytic (cc; n = 34) or immunocytic lymphoma (n = 124). The number of treatment failures and recurrences were clearly reduced. There were three prognostic steps in survival probability: 90% after seven years for stages IA-IVA of the cb/cc lymphoma as well as for the extranodal lymphoplasmocytoid and lymphoplasmocytic immunocytomas, stages I-IV of Ann Arbor, and stages 0-II of the Rai classifications. In the Rai stages III and IV these immunocytomas had a definitely worse prognosis, at 60%. Prognostically most unfavourable, at levels of around or below 30%, were the B forms of cb/cc lymphomas, all stages of centrocytoma and the polymorph-cell immunocytomas. The survival rate of the cb/cc lymphomas was increased by about 33%, compared with cases of Brill-Symmers' disease between 1970 and 1975. The alternating use of cytostatic combinations seems to be more favourable among the previously little affected centrocytomas and the polymorph-cell immunocytomas." @default.
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- W2412724246 date "2008-03-26" @default.
- W2412724246 modified "2023-09-23" @default.
- W2412724246 title "Prognostische Unterschiede bei niedrig-malignen Keimzentrumslymphomen und Immunozytomen: Beziehung zu histologischen Subtypen, Stadien und Therapie" @default.
- W2412724246 doi "https://doi.org/10.1055/s-2008-1069855" @default.
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