FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2412779310> ?p ?o ?g. }

• W2412779310 endingPage "532" @default.
• W2412779310 startingPage "527" @default.
• W2412779310 abstract "The gamma-glutamyl transpeptidase (GGT)-positive hyperplastic liver lesions which developed in the Fisher 344 rat 7 and 60 days following a single carcinogenic dose of diethylnitrosamine (DENA, 200 mg/kg body weight), short-term dietary exposure to 0.02% 2-acetylaminofluorene (AAF) to suppress the growth of normal hepatocytes, and partial hepatectomy to actuate rapid growth of DENA altered hepatocytes not suppressed by AFF, showed an increased activity of a kinase which specifically phosphorylates the ribosomal S6 protein in vitro. Sham-operated animals showed, on the contrary, no GGT-positive cells and low S6 kinase activity, under the same conditions. After partial hepatectomy, activation of S6 kinase and elevated levels of phosphorylated S6 protein in vitro were detected in the early phases of normal hepatocyte proliferation, during liver regeneration, in DENA-treated, GGT-negative preparations, when the selection agent AAF was omitted from the diet. The observed activation of S6 kinase in GGT-positive hepatocytes and/or liver nodules could represent an early manifestation of the enhanced proliferation of altered hepatocytes during tumor induction and/or promotion under these conditions." @default.
• W2412779310 created "2016-06-24" @default.
• W2412779310 creator A5030731416 @default.
• W2412779310 creator A5032382790 @default.
• W2412779310 creator A5041035657 @default.
• W2412779310 date "1989-12-01" @default.
• W2412779310 modified "2023-09-25" @default.
• W2412779310 title "Activation of a Ribosomal S6 Protein Kinase in Rapidly Emerging Diethylnitrosamine-Induced Gamma - Glut Amyltranspeptidase-Positive Hyperplastic Liver Lesions of the Rat" @default.
• W2412779310 cites W1536076450 @default.
• W2412779310 cites W1556948298 @default.
• W2412779310 cites W1608198953 @default.
• W2412779310 cites W1775749144 @default.
• W2412779310 cites W1979988236 @default.
• W2412779310 cites W2014459225 @default.
• W2412779310 cites W2020999475 @default.
• W2412779310 cites W2035691707 @default.
• W2412779310 cites W2039140238 @default.
• W2412779310 cites W2076416779 @default.
• W2412779310 cites W2092904403 @default.
• W2412779310 cites W2100837269 @default.
• W2412779310 cites W2116888647 @default.
• W2412779310 cites W2125038466 @default.
• W2412779310 cites W2140047977 @default.
• W2412779310 cites W2156872475 @default.
• W2412779310 cites W2162939439 @default.
• W2412779310 cites W4236599051 @default.
• W2412779310 cites W4247831151 @default.
• W2412779310 doi "https://doi.org/10.1177/030089168907500602" @default.
• W2412779310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2575815" @default.
• W2412779310 hasPublicationYear "1989" @default.
• W2412779310 type Work @default.
• W2412779310 sameAs 2412779310 @default.
• W2412779310 citedByCount "5" @default.
• W2412779310 crossrefType "journal-article" @default.
• W2412779310 hasAuthorship W2412779310A5030731416 @default.
• W2412779310 hasAuthorship W2412779310A5032382790 @default.
• W2412779310 hasAuthorship W2412779310A5041035657 @default.
• W2412779310 hasConcept C104317684 @default.
• W2412779310 hasConcept C114246631 @default.
• W2412779310 hasConcept C11960822 @default.
• W2412779310 hasConcept C126322002 @default.
• W2412779310 hasConcept C134018914 @default.
• W2412779310 hasConcept C171056886 @default.
• W2412779310 hasConcept C184235292 @default.
• W2412779310 hasConcept C185592680 @default.
• W2412779310 hasConcept C202751555 @default.
• W2412779310 hasConcept C2776200302 @default.
• W2412779310 hasConcept C2776795407 @default.
• W2412779310 hasConcept C2779838395 @default.
• W2412779310 hasConcept C2780122803 @default.
• W2412779310 hasConcept C2780926556 @default.
• W2412779310 hasConcept C55493867 @default.
• W2412779310 hasConcept C555283112 @default.
• W2412779310 hasConcept C71924100 @default.
• W2412779310 hasConcept C86803240 @default.
• W2412779310 hasConcept C87325107 @default.
• W2412779310 hasConcept C87644729 @default.
• W2412779310 hasConcept C95444343 @default.
• W2412779310 hasConcept C97029542 @default.
• W2412779310 hasConceptScore W2412779310C104317684 @default.
• W2412779310 hasConceptScore W2412779310C114246631 @default.
• W2412779310 hasConceptScore W2412779310C11960822 @default.
• W2412779310 hasConceptScore W2412779310C126322002 @default.
• W2412779310 hasConceptScore W2412779310C134018914 @default.
• W2412779310 hasConceptScore W2412779310C171056886 @default.
• W2412779310 hasConceptScore W2412779310C184235292 @default.
• W2412779310 hasConceptScore W2412779310C185592680 @default.
• W2412779310 hasConceptScore W2412779310C202751555 @default.
• W2412779310 hasConceptScore W2412779310C2776200302 @default.
• W2412779310 hasConceptScore W2412779310C2776795407 @default.
• W2412779310 hasConceptScore W2412779310C2779838395 @default.
• W2412779310 hasConceptScore W2412779310C2780122803 @default.
• W2412779310 hasConceptScore W2412779310C2780926556 @default.
• W2412779310 hasConceptScore W2412779310C55493867 @default.
• W2412779310 hasConceptScore W2412779310C555283112 @default.
• W2412779310 hasConceptScore W2412779310C71924100 @default.
• W2412779310 hasConceptScore W2412779310C86803240 @default.
• W2412779310 hasConceptScore W2412779310C87325107 @default.
• W2412779310 hasConceptScore W2412779310C87644729 @default.
• W2412779310 hasConceptScore W2412779310C95444343 @default.
• W2412779310 hasConceptScore W2412779310C97029542 @default.
• W2412779310 hasIssue "6" @default.
• W2412779310 hasLocation W24127793101 @default.
• W2412779310 hasLocation W24127793102 @default.
• W2412779310 hasOpenAccess W2412779310 @default.
• W2412779310 hasPrimaryLocation W24127793101 @default.
• W2412779310 hasRelatedWork W1873013205 @default.
• W2412779310 hasRelatedWork W1990159121 @default.
• W2412779310 hasRelatedWork W1996327145 @default.
• W2412779310 hasRelatedWork W2053593912 @default.
• W2412779310 hasRelatedWork W2068198215 @default.
• W2412779310 hasRelatedWork W2125038466 @default.
• W2412779310 hasRelatedWork W2161511101 @default.
• W2412779310 hasRelatedWork W2169311046 @default.
• W2412779310 hasRelatedWork W2400861590 @default.
• W2412779310 hasRelatedWork W2412779310 @default.
• W2412779310 hasVolume "75" @default.
• W2412779310 isParatext "false" @default.

• next