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- W2412878907 abstract "SUMMARY A combined distemper-hepatitis contagiosa vaccine (DTCV), consisting of living attenuated dog kidney tissue distemper virus and formalin-inactivated hepatitis virus (HCC), and an egg distemper vaccine (EV) were compared with regard to their immunizing capacity in dogs and ferrets. The DTCV was inferior as a vaccine in ferrets hut considerably superior in dogs. It is concluded that ferrets are not suitable as experimental animals for testing the immunizing capacity of vaccines intended for use in dogs. It is suggested that such tests should be performed in dogs. The inactivated hepatitis virus component in the combined vaccine caused the appearance of relatively high HI antibody titres and afforded protection against a challenge of 106 TCD50 of HCC vims 4 weeks after immunization." @default.
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- W2412878907 date "1965-10-01" @default.
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- W2412878907 title "Comparison between the Immunizing Effect in Dogs and Ferrets of Living Distemper Vaccines, Attenuated in Dog Tissue Cultures and Embryonated Eggs" @default.
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- W2412878907 doi "https://doi.org/10.1016/s0034-5288(18)34720-9" @default.
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