Matches in SemOpenAlex for { <https://semopenalex.org/work/W2412942056> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2412942056 endingPage "F1509" @default.
- W2412942056 startingPage "F1504" @default.
- W2412942056 abstract "In view of the potent vasoactive properties of platelet-activating factor (PAF), we investigated the renal hemodynamic effects of this lipid. C16-PAF (0.5-10 ng/kg) given as a bolus into the renal arterial circulation of pentobarbital sodium-anesthetized male Wistar rats produced a dose-dependent increase in renal blood flow (6-15%), before causing systemic hypotension. The PAF-induced renal vasodilation and systemic hypotension was independent of renal innervation, unaltered by eicosanoid synthesis inhibition with indomethacin or dexamethasone, unchanged by the nonselective dopamine-receptor antagonist haloperidol, but was abolished by the PAF-receptor antagonist, L-659,989. Non-hypotensive intrarenal PAF infusion at 0.5 ng.min-1.kg-1 caused an increase in renal blood flow. Thus PAF can cause renal vasodilation in the rat kidney that is PAF-receptor mediated and does not involve the sympathetic nervous system or the release of vasodilatory arachidonic acid metabolites or dopamine." @default.
- W2412942056 created "2016-06-24" @default.
- W2412942056 creator A5025147697 @default.
- W2412942056 creator A5075187095 @default.
- W2412942056 creator A5080584791 @default.
- W2412942056 date "1990-06-01" @default.
- W2412942056 modified "2023-09-27" @default.
- W2412942056 title "Platelet-activating factor is a renal vasodilator in the anesthetized rat" @default.
- W2412942056 doi "https://doi.org/10.1152/ajprenal.1990.258.6.f1504" @default.
- W2412942056 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2360650" @default.
- W2412942056 hasPublicationYear "1990" @default.
- W2412942056 type Work @default.
- W2412942056 sameAs 2412942056 @default.
- W2412942056 citedByCount "7" @default.
- W2412942056 countsByYear W24129420562015 @default.
- W2412942056 crossrefType "journal-article" @default.
- W2412942056 hasAuthorship W2412942056A5025147697 @default.
- W2412942056 hasAuthorship W2412942056A5075187095 @default.
- W2412942056 hasAuthorship W2412942056A5080584791 @default.
- W2412942056 hasConcept C120770815 @default.
- W2412942056 hasConcept C126322002 @default.
- W2412942056 hasConcept C134018914 @default.
- W2412942056 hasConcept C142225936 @default.
- W2412942056 hasConcept C170493617 @default.
- W2412942056 hasConcept C185592680 @default.
- W2412942056 hasConcept C2776885963 @default.
- W2412942056 hasConcept C2778122271 @default.
- W2412942056 hasConcept C2779020240 @default.
- W2412942056 hasConcept C2780091579 @default.
- W2412942056 hasConcept C2781073237 @default.
- W2412942056 hasConcept C71924100 @default.
- W2412942056 hasConcept C98274493 @default.
- W2412942056 hasConceptScore W2412942056C120770815 @default.
- W2412942056 hasConceptScore W2412942056C126322002 @default.
- W2412942056 hasConceptScore W2412942056C134018914 @default.
- W2412942056 hasConceptScore W2412942056C142225936 @default.
- W2412942056 hasConceptScore W2412942056C170493617 @default.
- W2412942056 hasConceptScore W2412942056C185592680 @default.
- W2412942056 hasConceptScore W2412942056C2776885963 @default.
- W2412942056 hasConceptScore W2412942056C2778122271 @default.
- W2412942056 hasConceptScore W2412942056C2779020240 @default.
- W2412942056 hasConceptScore W2412942056C2780091579 @default.
- W2412942056 hasConceptScore W2412942056C2781073237 @default.
- W2412942056 hasConceptScore W2412942056C71924100 @default.
- W2412942056 hasConceptScore W2412942056C98274493 @default.
- W2412942056 hasIssue "6" @default.
- W2412942056 hasLocation W24129420561 @default.
- W2412942056 hasLocation W24129420562 @default.
- W2412942056 hasOpenAccess W2412942056 @default.
- W2412942056 hasPrimaryLocation W24129420561 @default.
- W2412942056 hasRelatedWork W1976219263 @default.
- W2412942056 hasRelatedWork W1981626491 @default.
- W2412942056 hasRelatedWork W1992689150 @default.
- W2412942056 hasRelatedWork W2058127676 @default.
- W2412942056 hasRelatedWork W2083576828 @default.
- W2412942056 hasRelatedWork W2110143838 @default.
- W2412942056 hasRelatedWork W2393521223 @default.
- W2412942056 hasRelatedWork W2404152533 @default.
- W2412942056 hasRelatedWork W2413658046 @default.
- W2412942056 hasRelatedWork W2563938602 @default.
- W2412942056 hasVolume "258" @default.
- W2412942056 isParatext "false" @default.
- W2412942056 isRetracted "false" @default.
- W2412942056 magId "2412942056" @default.
- W2412942056 workType "article" @default.