Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413016364> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2413016364 endingPage "97" @default.
- W2413016364 startingPage "87" @default.
- W2413016364 abstract "Immunohistochemistry using antibodies to tyrosine hydroxylase (TH), a rate-limiting enzyme which catalyzes the initial step in the catecholamine synthesizing pathway, has been widely accepted as one of the methods for identification of catecholamine neurons in the nervous system. In the present study, we performed immunohistochemical examination to elucidate the distribution of catecholamine neurons in brain stem of human fetuses. The brain stems were obtained from 8 human fetuses (CRL: 120-275 mm, GA: 15-27 wks) 1-3 h after death following therapeutic or spontaneous abortion. They were immediately fixed with 4% paraformaldehyde in 0.1 M phosphate buffer, pH 7.4, dehydrated with graded ethanol, and embedded in paraffin. Serial 6 microns sections were cut from 7 different levels of the brain stem of each fetus. These sections were stained by peroxidase-antiperoxidase (PAP) technique using TH antisera. The TH antisera used were raised in rabbits by injecting purified TH from bovine adrenal medulla. The preparation and the specificity of TH antisera were described in detail elsewhere (Nakashima et al, 1983). Catecholamine neurons were clearly demonstrated in the brain stem of all fetuses. They could be recognized as catecholamine cell groups in the same manner as is done in experimental mammals. Among these cell groups, the catecholamine neurons showed distinct cytological features in shape and size. The distribution of catecholamine positive neurons in the brain stem was almost the same in the 8 human fetuses, and an atlas was given with anatomical explanation under the terminology of Olszewski and Baxter (1982) for the human brain stem. In the mesencephalon, a large number of catecholamine neurons lay in the nucleus substantiae nigrae, pars compacta, the nucleus paranigralis, the middle of the ventral tegmentum and the tractus tegmentalis centralis, and fewer catecholamine neurons were scattered in the other tegmental area. In addition, a group of small catecholamine neurons was located in the griseum centrale mesencephali near the aqueduct. In the pons, catecholamine neurons occurred mainly in the nucleus locus coeruleus and the nucleus subcoeruleus. A band of TH-positive neurons extended from the nucleus locus coeruleus to the dorsolateral tegmentum, and further to the roof of the fourth ventricle. Occasional catecholamine neurons were present in the area medial to the upper portion of the nucleus locus coeruleus. More caudally, a small number of catecholamine neurons were scattered in the area medial to the nervus facialis and adjacent to the nucleus facialis and the nucleus olivaris superior.(ABSTRACT TRUNCATED AT 400 WORDS)" @default.
- W2413016364 created "2016-06-24" @default.
- W2413016364 creator A5010638689 @default.
- W2413016364 creator A5023470663 @default.
- W2413016364 creator A5031815891 @default.
- W2413016364 creator A5045222817 @default.
- W2413016364 creator A5079684505 @default.
- W2413016364 date "1986-01-01" @default.
- W2413016364 modified "2023-09-23" @default.
- W2413016364 title "[Topography of the catecholamine neurons in the brain stem of the human fetus: an immunohistochemical study using antibodies to tyrosine hydroxylase]." @default.
- W2413016364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2870726" @default.
- W2413016364 hasPublicationYear "1986" @default.
- W2413016364 type Work @default.
- W2413016364 sameAs 2413016364 @default.
- W2413016364 citedByCount "2" @default.
- W2413016364 crossrefType "journal-article" @default.
- W2413016364 hasAuthorship W2413016364A5010638689 @default.
- W2413016364 hasAuthorship W2413016364A5023470663 @default.
- W2413016364 hasAuthorship W2413016364A5031815891 @default.
- W2413016364 hasAuthorship W2413016364A5045222817 @default.
- W2413016364 hasAuthorship W2413016364A5079684505 @default.
- W2413016364 hasConcept C126322002 @default.
- W2413016364 hasConcept C134018914 @default.
- W2413016364 hasConcept C142724271 @default.
- W2413016364 hasConcept C159167319 @default.
- W2413016364 hasConcept C159654299 @default.
- W2413016364 hasConcept C169760540 @default.
- W2413016364 hasConcept C172680121 @default.
- W2413016364 hasConcept C203014093 @default.
- W2413016364 hasConcept C204232928 @default.
- W2413016364 hasConcept C2775894120 @default.
- W2413016364 hasConcept C2777597313 @default.
- W2413016364 hasConcept C2777670902 @default.
- W2413016364 hasConcept C2779234561 @default.
- W2413016364 hasConcept C513476851 @default.
- W2413016364 hasConcept C54355233 @default.
- W2413016364 hasConcept C71924100 @default.
- W2413016364 hasConcept C86803240 @default.
- W2413016364 hasConceptScore W2413016364C126322002 @default.
- W2413016364 hasConceptScore W2413016364C134018914 @default.
- W2413016364 hasConceptScore W2413016364C142724271 @default.
- W2413016364 hasConceptScore W2413016364C159167319 @default.
- W2413016364 hasConceptScore W2413016364C159654299 @default.
- W2413016364 hasConceptScore W2413016364C169760540 @default.
- W2413016364 hasConceptScore W2413016364C172680121 @default.
- W2413016364 hasConceptScore W2413016364C203014093 @default.
- W2413016364 hasConceptScore W2413016364C204232928 @default.
- W2413016364 hasConceptScore W2413016364C2775894120 @default.
- W2413016364 hasConceptScore W2413016364C2777597313 @default.
- W2413016364 hasConceptScore W2413016364C2777670902 @default.
- W2413016364 hasConceptScore W2413016364C2779234561 @default.
- W2413016364 hasConceptScore W2413016364C513476851 @default.
- W2413016364 hasConceptScore W2413016364C54355233 @default.
- W2413016364 hasConceptScore W2413016364C71924100 @default.
- W2413016364 hasConceptScore W2413016364C86803240 @default.
- W2413016364 hasIssue "1" @default.
- W2413016364 hasLocation W24130163641 @default.
- W2413016364 hasOpenAccess W2413016364 @default.
- W2413016364 hasPrimaryLocation W24130163641 @default.
- W2413016364 hasRelatedWork W128811213 @default.
- W2413016364 hasRelatedWork W2000776761 @default.
- W2413016364 hasRelatedWork W2014160643 @default.
- W2413016364 hasRelatedWork W2078052498 @default.
- W2413016364 hasRelatedWork W2085357088 @default.
- W2413016364 hasRelatedWork W2091536676 @default.
- W2413016364 hasRelatedWork W2097047907 @default.
- W2413016364 hasRelatedWork W2296960573 @default.
- W2413016364 hasRelatedWork W2471143780 @default.
- W2413016364 hasRelatedWork W2471413691 @default.
- W2413016364 hasVolume "38" @default.
- W2413016364 isParatext "false" @default.
- W2413016364 isRetracted "false" @default.
- W2413016364 magId "2413016364" @default.
- W2413016364 workType "article" @default.