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- W2413051212 endingPage "146" @default.
- W2413051212 startingPage "145" @default.
- W2413051212 abstract "目的：比較小鼠骨髓來源樹突狀細胞(DC)和DC 2.4形態與功能。方法：無菌製備C57BC/6小鼠骨髓細胞，通過半粘附法獲得DC前體，在粒細胞巨噬細胞集落刺激因子(GM-CSF)和白細胞介素(IL-4)協同誘導下培育。用脂多糖(LPS)和腫瘤壞死因子(TNF-α)刺激DC 2.4和第7天後小鼠骨髓來源DC 48h，檢測細胞因子IL-12濃度及細胞表面標誌CD11c，CD80，CD86，MHCⅡ。結果：DC 2.4和小鼠骨髓來源DC形態呈星形、梭形和多角形；DC 2.4為不成熟DC，但在LPS和TNF-α刺激下，細胞表面標誌物陽性率及IL-12濃度明顯增加。結論：小鼠骨髓來源所得細胞的形態和功能符合DC；用LPS和TNF-α刺激DC 2.4可以使DC向成熟方向轉化。" @default.
- W2413051212 created "2016-06-24" @default.
- W2413051212 creator A5035730033 @default.
- W2413051212 creator A5053774925 @default.
- W2413051212 creator A5057715483 @default.
- W2413051212 date "2005-06-25" @default.
- W2413051212 modified "2023-09-28" @default.
- W2413051212 title "小鼠骨髓來源樹突狀細胞和DC 2.4形態與功能比較" @default.
- W2413051212 hasPublicationYear "2005" @default.
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