Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413109905> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2413109905 endingPage "3" @default.
- W2413109905 startingPage "189" @default.
- W2413109905 abstract "Phagocytosis is the process where specific cells, phagocytes, ingest foreign material, include it in a cytoplasmatic vacuole, called phagosome, and destroy it. The function of phagocytosis in the immune response has been underevaluated for a very long time. Phagocytosis however, appears to be more and more important in our defense against infection and cancer. The uremic patient presents a well known and increased tendency for infectious disease as well as an increased incidence of cancer. Modern methodology for investigation of phagocytic function consists of: 1. measuring the respiratory burst during phagocytosis; by examining the radio-active CO2 production during the glucose metabolization of phagocytosis. 2. During the chemical reaction of the respiratory burst light is produced. This chemiluminescence can be measured in a Lumetron. In uremia the registration of that chemiluminescence can however be disturbed by the presence of uremic toxins, acting as scavengers of free radicals. 3. Measurement of interleukin-1, interleukin-6 or tumor necrosis factor production during phagocytosis. In the present study, we investigated glucose metabolization and radioactive CO2 production without stimulation and after a challenge with Latex, Zymosan or Staphylococcus Aureus. All tests have been performed on 50 microliter whole blood samples. The following uremic situations have been investigated: 1. Several degrees of increasing renal failure. 2. First weeks of hemodialysis maintenance treatment. 3. Hemodialysis session. 4. Course of hemodialysis maintenance treatment. 5. Continuous ambulatory peritoneal dialysis (CAPD) and renal transplantation. 6. Changes after chemical stimulation by a cephalosporin (cefodizime (R)). The Authors report their detailed results of these investigations and conclude as follows: --uremia is a prototype of acquired immune deficiency. --Contact with bio-incompatible membranes during hemodialysis is disastrous for phagocytosis. --Other toxins than the classical urea or creatinine are apparently responsible for the phagocytic disturbances. --Stimulations of phagocytosis with medication such as the cephalosporin, Cefodizime(R) (Hoechst) is possible." @default.
- W2413109905 created "2016-06-24" @default.
- W2413109905 creator A5036524734 @default.
- W2413109905 creator A5083345780 @default.
- W2413109905 date "1991-01-01" @default.
- W2413109905 modified "2023-09-23" @default.
- W2413109905 title "[Phagocyte function in uremic patients]." @default.
- W2413109905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1927026" @default.
- W2413109905 hasPublicationYear "1991" @default.
- W2413109905 type Work @default.
- W2413109905 sameAs 2413109905 @default.
- W2413109905 citedByCount "0" @default.
- W2413109905 crossrefType "journal-article" @default.
- W2413109905 hasAuthorship W2413109905A5036524734 @default.
- W2413109905 hasAuthorship W2413109905A5083345780 @default.
- W2413109905 hasConcept C126322002 @default.
- W2413109905 hasConcept C160448771 @default.
- W2413109905 hasConcept C181199279 @default.
- W2413109905 hasConcept C185592680 @default.
- W2413109905 hasConcept C203014093 @default.
- W2413109905 hasConcept C2776635150 @default.
- W2413109905 hasConcept C2779978075 @default.
- W2413109905 hasConcept C2780795997 @default.
- W2413109905 hasConcept C55493867 @default.
- W2413109905 hasConcept C71924100 @default.
- W2413109905 hasConcept C86803240 @default.
- W2413109905 hasConcept C8891405 @default.
- W2413109905 hasConcept C89423630 @default.
- W2413109905 hasConcept C99971728 @default.
- W2413109905 hasConceptScore W2413109905C126322002 @default.
- W2413109905 hasConceptScore W2413109905C160448771 @default.
- W2413109905 hasConceptScore W2413109905C181199279 @default.
- W2413109905 hasConceptScore W2413109905C185592680 @default.
- W2413109905 hasConceptScore W2413109905C203014093 @default.
- W2413109905 hasConceptScore W2413109905C2776635150 @default.
- W2413109905 hasConceptScore W2413109905C2779978075 @default.
- W2413109905 hasConceptScore W2413109905C2780795997 @default.
- W2413109905 hasConceptScore W2413109905C55493867 @default.
- W2413109905 hasConceptScore W2413109905C71924100 @default.
- W2413109905 hasConceptScore W2413109905C86803240 @default.
- W2413109905 hasConceptScore W2413109905C8891405 @default.
- W2413109905 hasConceptScore W2413109905C89423630 @default.
- W2413109905 hasConceptScore W2413109905C99971728 @default.
- W2413109905 hasIssue "3" @default.
- W2413109905 hasLocation W24131099051 @default.
- W2413109905 hasOpenAccess W2413109905 @default.
- W2413109905 hasPrimaryLocation W24131099051 @default.
- W2413109905 hasRelatedWork W1914469980 @default.
- W2413109905 hasRelatedWork W2014103626 @default.
- W2413109905 hasRelatedWork W2020732818 @default.
- W2413109905 hasRelatedWork W2026378555 @default.
- W2413109905 hasRelatedWork W2052866694 @default.
- W2413109905 hasRelatedWork W2085028693 @default.
- W2413109905 hasRelatedWork W2105428329 @default.
- W2413109905 hasRelatedWork W2145408997 @default.
- W2413109905 hasRelatedWork W40904356 @default.
- W2413109905 hasRelatedWork W804075373 @default.
- W2413109905 hasVolume "53" @default.
- W2413109905 isParatext "false" @default.
- W2413109905 isRetracted "false" @default.
- W2413109905 magId "2413109905" @default.
- W2413109905 workType "article" @default.