Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413137588> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2413137588 endingPage "831" @default.
- W2413137588 startingPage "826" @default.
- W2413137588 abstract "Background/Aims: Thyroid disorders are common dysfunctions during HCV infection and IFN-therapy. The aim of the study was to evaluate the general risk of thyroid disorders' development in chronic HCV-infected patients and their possible relationship with HCV genotype, type of used IFN-alpha and viral response. Methodology: A study was performed in 89 patients with chronic hepatitis C (57 males, 32 females) and 25 healthy subjects. All HCV-infected patients were treated by IFN-alpha and RBV for a period depending on the HCV genotype. Hematological parameters, liver and thyroid function tests were analyzed. Serum Tpo-Ab and TG-Ab were detected by semiquantitative ELISA. In statistical analyses U Mann-Whitney and Spearman correlation tests were used. A p value <0.05 was considered significant. Results: Twelve (13.5%) CHC patients developed thyroid disorders during IFN-alpha therapy. Thyroid disorders were more often detected in females, in 3a-genotype-infection and in patients treated with natural leukocyte IFN-alpha. Seven (7,6%) Tpo-Ab and/or TG-Ab positive patients were noticed. Four of them (57.1%) developed hypothyroidism during IFN-alpha therapy. Conclusion: This study demonstrated low effect of IFN-alpha therapy on thyroid disorders development and on TPO-Ab and TG-Ab serum level in chronic HCV-infected patients." @default.
- W2413137588 created "2016-06-24" @default.
- W2413137588 creator A5022459461 @default.
- W2413137588 creator A5058746547 @default.
- W2413137588 creator A5077813829 @default.
- W2413137588 date "2010-07-01" @default.
- W2413137588 modified "2023-09-23" @default.
- W2413137588 title "Thyroid dysfunction in antiviral therapy of chronic hepatitis C." @default.
- W2413137588 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21033237" @default.
- W2413137588 hasPublicationYear "2010" @default.
- W2413137588 type Work @default.
- W2413137588 sameAs 2413137588 @default.
- W2413137588 citedByCount "3" @default.
- W2413137588 countsByYear W24131375882013 @default.
- W2413137588 countsByYear W24131375882015 @default.
- W2413137588 countsByYear W24131375882016 @default.
- W2413137588 crossrefType "journal-article" @default.
- W2413137588 hasAuthorship W2413137588A5022459461 @default.
- W2413137588 hasAuthorship W2413137588A5058746547 @default.
- W2413137588 hasAuthorship W2413137588A5077813829 @default.
- W2413137588 hasConcept C104317684 @default.
- W2413137588 hasConcept C126322002 @default.
- W2413137588 hasConcept C135763542 @default.
- W2413137588 hasConcept C203014093 @default.
- W2413137588 hasConcept C2522874641 @default.
- W2413137588 hasConcept C2776178377 @default.
- W2413137588 hasConcept C2776455275 @default.
- W2413137588 hasConcept C2909179924 @default.
- W2413137588 hasConcept C3020491458 @default.
- W2413137588 hasConcept C526584372 @default.
- W2413137588 hasConcept C55493867 @default.
- W2413137588 hasConcept C71924100 @default.
- W2413137588 hasConcept C86803240 @default.
- W2413137588 hasConcept C90924648 @default.
- W2413137588 hasConceptScore W2413137588C104317684 @default.
- W2413137588 hasConceptScore W2413137588C126322002 @default.
- W2413137588 hasConceptScore W2413137588C135763542 @default.
- W2413137588 hasConceptScore W2413137588C203014093 @default.
- W2413137588 hasConceptScore W2413137588C2522874641 @default.
- W2413137588 hasConceptScore W2413137588C2776178377 @default.
- W2413137588 hasConceptScore W2413137588C2776455275 @default.
- W2413137588 hasConceptScore W2413137588C2909179924 @default.
- W2413137588 hasConceptScore W2413137588C3020491458 @default.
- W2413137588 hasConceptScore W2413137588C526584372 @default.
- W2413137588 hasConceptScore W2413137588C55493867 @default.
- W2413137588 hasConceptScore W2413137588C71924100 @default.
- W2413137588 hasConceptScore W2413137588C86803240 @default.
- W2413137588 hasConceptScore W2413137588C90924648 @default.
- W2413137588 hasIssue "101" @default.
- W2413137588 hasLocation W24131375881 @default.
- W2413137588 hasLocation W24131375882 @default.
- W2413137588 hasOpenAccess W2413137588 @default.
- W2413137588 hasPrimaryLocation W24131375881 @default.
- W2413137588 hasRelatedWork W1964005894 @default.
- W2413137588 hasRelatedWork W2001302624 @default.
- W2413137588 hasRelatedWork W2007705954 @default.
- W2413137588 hasRelatedWork W2010044342 @default.
- W2413137588 hasRelatedWork W2014282491 @default.
- W2413137588 hasRelatedWork W2019429013 @default.
- W2413137588 hasRelatedWork W2034207313 @default.
- W2413137588 hasRelatedWork W2063171103 @default.
- W2413137588 hasRelatedWork W2066860778 @default.
- W2413137588 hasRelatedWork W2071053681 @default.
- W2413137588 hasRelatedWork W2096880742 @default.
- W2413137588 hasRelatedWork W2097071522 @default.
- W2413137588 hasRelatedWork W2109949338 @default.
- W2413137588 hasRelatedWork W2117903190 @default.
- W2413137588 hasRelatedWork W2140057099 @default.
- W2413137588 hasRelatedWork W2143425175 @default.
- W2413137588 hasRelatedWork W2311404453 @default.
- W2413137588 hasRelatedWork W2351581295 @default.
- W2413137588 hasRelatedWork W2376102736 @default.
- W2413137588 hasRelatedWork W2394199658 @default.
- W2413137588 hasVolume "57" @default.
- W2413137588 isParatext "false" @default.
- W2413137588 isRetracted "false" @default.
- W2413137588 magId "2413137588" @default.
- W2413137588 workType "article" @default.