FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413303725> ?p ?o ?g. }

• W2413303725 endingPage "139" @default.
• W2413303725 startingPage "139" @default.
• W2413303725 abstract "Chronic hepatitis C virus (HCV) infection affects 80-160 million people worldwide and is one of the leading causes of chronic liver disease. It is only a few years ago that standard treatment regimes were based on pegylated interferon alpha and ribavirin. However, treatment of HCV has undergone a revolutionary change in recent years. The admission of the nucleotide polymerase inhibitor Sofosbuvir enabled an interferon-free regimen with direct antiviral agents (DAA). Meanwhile seven DAAs are available and can be applied in several combinations for 8 to 24 wk depending on HCV genotype and patient characteristics such as cirrhosis and chronic renal failure. High rates of sustained virological response (SVR) rates can be achieved with these novel drugs. Even in difficult to treat populations such as patients with liver cirrhosis, HCV-human immunodeficiency virus co-infections, after liver transplantion, or with chronic kidney disease comparable high rates of SVR can be achieved. The anticipated 2(nd) generation DAAs are strikingly effective in patients so far classified as difficult to treat including decompensated liver cirrhosis or post-transplant patients. These 2(nd) generations DAAs will have higher resistance barriers, higher antiviral effects and a pan-genotypic spectrum. This review highlights the current state of the art of antiviral treatment in hepatitis C and gives an outlook for upcoming therapies." @default.
• W2413303725 created "2016-06-24" @default.
• W2413303725 creator A5046729324 @default.
• W2413303725 creator A5053251591 @default.
• W2413303725 creator A5066916107 @default.
• W2413303725 creator A5081840796 @default.
• W2413303725 date "2016-01-01" @default.
• W2413303725 modified "2023-09-26" @default.
• W2413303725 title "Advances in hepatitis C therapy: What is the current state - what come's next?" @default.
• W2413303725 cites W1413845340 @default.
• W2413303725 cites W1510051491 @default.
• W2413303725 cites W1804925654 @default.
• W2413303725 cites W1881009043 @default.
• W2413303725 cites W1881390415 @default.
• W2413303725 cites W1908153784 @default.
• W2413303725 cites W1967348642 @default.
• W2413303725 cites W1973675889 @default.
• W2413303725 cites W1981513035 @default.
• W2413303725 cites W2004560175 @default.
• W2413303725 cites W2015740979 @default.
• W2413303725 cites W2022687771 @default.
• W2413303725 cites W2030470608 @default.
• W2413303725 cites W2035804055 @default.
• W2413303725 cites W2037648619 @default.
• W2413303725 cites W2043193067 @default.
• W2413303725 cites W2046658390 @default.
• W2413303725 cites W2047911275 @default.
• W2413303725 cites W2048778984 @default.
• W2413303725 cites W2069465518 @default.
• W2413303725 cites W2078251659 @default.
• W2413303725 cites W2081897332 @default.
• W2413303725 cites W2092646281 @default.
• W2413303725 cites W2113428683 @default.
• W2413303725 cites W2114985397 @default.
• W2413303725 cites W2120733999 @default.
• W2413303725 cites W2125963799 @default.
• W2413303725 cites W2126689013 @default.
• W2413303725 cites W2126956071 @default.
• W2413303725 cites W2141214317 @default.
• W2413303725 cites W2143559032 @default.
• W2413303725 cites W2149722964 @default.
• W2413303725 cites W2150652264 @default.
• W2413303725 cites W2151063300 @default.
• W2413303725 cites W2151554611 @default.
• W2413303725 cites W2161578383 @default.
• W2413303725 cites W2164466220 @default.
• W2413303725 cites W2189833010 @default.
• W2413303725 cites W2196623670 @default.
• W2413303725 cites W2213494675 @default.
• W2413303725 cites W2222306685 @default.
• W2413303725 cites W2268397669 @default.
• W2413303725 cites W2287448501 @default.
• W2413303725 cites W2315634424 @default.
• W2413303725 cites W3114412741 @default.
• W2413303725 cites W4211077792 @default.
• W2413303725 cites W4241616429 @default.
• W2413303725 cites W971519378 @default.
• W2413303725 doi "https://doi.org/10.4254/wjh.v8.i3.139" @default.
• W2413303725 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4724577" @default.
• W2413303725 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26839638" @default.
• W2413303725 hasPublicationYear "2016" @default.
• W2413303725 type Work @default.
• W2413303725 sameAs 2413303725 @default.
• W2413303725 citedByCount "86" @default.
• W2413303725 countsByYear W24133037252015 @default.
• W2413303725 countsByYear W24133037252016 @default.
• W2413303725 countsByYear W24133037252017 @default.
• W2413303725 countsByYear W24133037252018 @default.
• W2413303725 countsByYear W24133037252019 @default.
• W2413303725 countsByYear W24133037252020 @default.
• W2413303725 countsByYear W24133037252022 @default.
• W2413303725 countsByYear W24133037252023 @default.
• W2413303725 crossrefType "journal-article" @default.
• W2413303725 hasAuthorship W2413303725A5046729324 @default.
• W2413303725 hasAuthorship W2413303725A5053251591 @default.
• W2413303725 hasAuthorship W2413303725A5066916107 @default.
• W2413303725 hasAuthorship W2413303725A5081840796 @default.
• W2413303725 hasBestOaLocation W24133037251 @default.
• W2413303725 hasConcept C126322002 @default.
• W2413303725 hasConcept C159047783 @default.
• W2413303725 hasConcept C203014093 @default.
• W2413303725 hasConcept C2522874641 @default.
• W2413303725 hasConcept C2776178377 @default.
• W2413303725 hasConcept C2776408679 @default.
• W2413303725 hasConcept C2776455275 @default.
• W2413303725 hasConcept C2776461080 @default.
• W2413303725 hasConcept C2777075537 @default.
• W2413303725 hasConcept C2777214474 @default.
• W2413303725 hasConcept C2778390639 @default.
• W2413303725 hasConcept C2779102576 @default.
• W2413303725 hasConcept C2779609443 @default.
• W2413303725 hasConcept C2780040827 @default.
• W2413303725 hasConcept C2781413609 @default.
• W2413303725 hasConcept C2911091166 @default.
• W2413303725 hasConcept C71924100 @default.
• W2413303725 hasConcept C90924648 @default.
• W2413303725 hasConceptScore W2413303725C126322002 @default.
• W2413303725 hasConceptScore W2413303725C159047783 @default.

• next