Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413334876> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2413334876 endingPage "8" @default.
- W2413334876 startingPage "214" @default.
- W2413334876 abstract "Very Late Antigen-6 (VLA-6) is a laminin receptor found on T cells, macrophages and platelets and may function as an activation antigen. Here we describe that two monoclonal antibodies (mAb) targeting the VLA-6 alpha-chain are capable of inducing homotypic aggregation of murine T-cell lines (3A9 and C10 cells). 3A9 and C10 cells are of the memory phenotype (CD4+, CD8-, CD44+, CD45+) and express VLA-6 abundantly. The VLA-6-induced aggregation is temperature dependent, energy requiring, and involves the cytoskeleton. In addition, divalent cations (Ca2+ and Mg2+) are also necessary for aggregation. The VLA-6-induced aggregation is not inhibited with mAb targeting the LFA-1/ICAM-1, VLA-4/VCAM-1 and CD2/LFA-3 adhesion pairs. We conclude that VLA-6 has a broader function and can serve as an activation molecule, triggering homotypic aggregation of T-cell subsets." @default.
- W2413334876 created "2016-06-24" @default.
- W2413334876 creator A5082173412 @default.
- W2413334876 date "1992-10-01" @default.
- W2413334876 modified "2023-10-18" @default.
- W2413334876 title "Monoclonal antibodies to the murine VLA-6 alpha-chain trigger homotypic lymphocyte aggregation." @default.
- W2413334876 cites W1492908069 @default.
- W2413334876 cites W1506270602 @default.
- W2413334876 cites W1508062973 @default.
- W2413334876 cites W1511533680 @default.
- W2413334876 cites W1519475892 @default.
- W2413334876 cites W1578883193 @default.
- W2413334876 cites W1588115842 @default.
- W2413334876 cites W1591577036 @default.
- W2413334876 cites W1762152820 @default.
- W2413334876 cites W1782927503 @default.
- W2413334876 cites W1919103296 @default.
- W2413334876 cites W1965198099 @default.
- W2413334876 cites W1988645163 @default.
- W2413334876 cites W2051811193 @default.
- W2413334876 cites W2086487142 @default.
- W2413334876 cites W2116178029 @default.
- W2413334876 cites W2135121318 @default.
- W2413334876 cites W2150533109 @default.
- W2413334876 cites W2171086365 @default.
- W2413334876 cites W2399600848 @default.
- W2413334876 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1421639" @default.
- W2413334876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1427976" @default.
- W2413334876 hasPublicationYear "1992" @default.
- W2413334876 type Work @default.
- W2413334876 sameAs 2413334876 @default.
- W2413334876 citedByCount "1" @default.
- W2413334876 crossrefType "journal-article" @default.
- W2413334876 hasAuthorship W2413334876A5082173412 @default.
- W2413334876 hasConcept C147483822 @default.
- W2413334876 hasConcept C1491633281 @default.
- W2413334876 hasConcept C153911025 @default.
- W2413334876 hasConcept C159654299 @default.
- W2413334876 hasConcept C167672396 @default.
- W2413334876 hasConcept C185592680 @default.
- W2413334876 hasConcept C195687474 @default.
- W2413334876 hasConcept C203014093 @default.
- W2413334876 hasConcept C2776090121 @default.
- W2413334876 hasConcept C2778593620 @default.
- W2413334876 hasConcept C542903549 @default.
- W2413334876 hasConcept C55493867 @default.
- W2413334876 hasConcept C86803240 @default.
- W2413334876 hasConcept C8891405 @default.
- W2413334876 hasConcept C95444343 @default.
- W2413334876 hasConceptScore W2413334876C147483822 @default.
- W2413334876 hasConceptScore W2413334876C1491633281 @default.
- W2413334876 hasConceptScore W2413334876C153911025 @default.
- W2413334876 hasConceptScore W2413334876C159654299 @default.
- W2413334876 hasConceptScore W2413334876C167672396 @default.
- W2413334876 hasConceptScore W2413334876C185592680 @default.
- W2413334876 hasConceptScore W2413334876C195687474 @default.
- W2413334876 hasConceptScore W2413334876C203014093 @default.
- W2413334876 hasConceptScore W2413334876C2776090121 @default.
- W2413334876 hasConceptScore W2413334876C2778593620 @default.
- W2413334876 hasConceptScore W2413334876C542903549 @default.
- W2413334876 hasConceptScore W2413334876C55493867 @default.
- W2413334876 hasConceptScore W2413334876C86803240 @default.
- W2413334876 hasConceptScore W2413334876C8891405 @default.
- W2413334876 hasConceptScore W2413334876C95444343 @default.
- W2413334876 hasIssue "2" @default.
- W2413334876 hasLocation W24133348761 @default.
- W2413334876 hasOpenAccess W2413334876 @default.
- W2413334876 hasPrimaryLocation W24133348761 @default.
- W2413334876 hasRelatedWork W1943797027 @default.
- W2413334876 hasRelatedWork W1983084765 @default.
- W2413334876 hasRelatedWork W1983672032 @default.
- W2413334876 hasRelatedWork W2009889818 @default.
- W2413334876 hasRelatedWork W2038126255 @default.
- W2413334876 hasRelatedWork W2064089409 @default.
- W2413334876 hasRelatedWork W2073262237 @default.
- W2413334876 hasRelatedWork W2153130739 @default.
- W2413334876 hasRelatedWork W2368460920 @default.
- W2413334876 hasRelatedWork W2380360044 @default.
- W2413334876 hasVolume "77" @default.
- W2413334876 isParatext "false" @default.
- W2413334876 isRetracted "false" @default.
- W2413334876 magId "2413334876" @default.
- W2413334876 workType "article" @default.