Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413362489> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2413362489 abstract "SummaryA virus was isolated from the blood of 6 out of 119 persons living in Guaroa, eastern Columbia. The locality is a recent settement situated at the edge of a natural savannah in the vicinity of a stretch of tropical rain forest. There is evidence that the agent isolated was the same in five of these persons. Serological studies showed that this agent was not identical with any of the 36 different anthropod-borne viruses with which it was compared, nor, in view of the known cross relationships among members of a group, could any evidence be found indicating that the virus belongs in groups A, B, or C. Our serological studies indicate that the virus is not related to Anopheles A, Anopheles B, and Wyeomyia. The conclusion derived from the immunological studies indicated that this was a new agent, to which the name Guaroa was given.A distant relationship was found between Guaroa and California encephalitis virus; this very slight overlap was detected by HI, but not by CF, and in one direction only. Although California immune sera inhibited a Guaroa antigen, Guaroa sera failed to inhibit a California antigen. Additional studies are clearly indicated to elucidate this crossing.Guaroa virus is pathogenic for white mice, regardless of age, when inoculated by the intracerebral route. When the subcutaneous route is used, it produces fatal infections in baby mice, but not in adults. Two rhesus monkeys inoculated subcutaneously and intradermally with the human sera from which the viruses were isolated, showed viremia and immunological conversion, but none developed fever or any clinical disease.Guaroa virus was isolated from persons who, at the time of the bleeding, did not complain of being sick. Four of these individuals apparently continued to enjoy good health during the month following the isolation of the virus. One person had a mild febrile illness lasting two days which started on the second day after the bleeding. It was not possible to continue the study of the sixth individual.A large proportion of residents of Guaroa was found to have neutralizing antibodies for Guaroa virus, which indicates that the agent was very prevalent there." @default.
- W2413362489 created "2016-06-24" @default.
- W2413362489 creator A5049603767 @default.
- W2413362489 creator A5077249193 @default.
- W2413362489 creator A5084720605 @default.
- W2413362489 creator A5004798262 @default.
- W2413362489 date "1959-09-01" @default.
- W2413362489 modified "2023-09-27" @default.
- W2413362489 title "Guaroa Virus, a New Agent Isolated in Colombia, South America" @default.
- W2413362489 doi "https://doi.org/10.4269/ajtmh.1959.8.604" @default.
- W2413362489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13851794" @default.
- W2413362489 hasPublicationYear "1959" @default.
- W2413362489 type Work @default.
- W2413362489 sameAs 2413362489 @default.
- W2413362489 citedByCount "17" @default.
- W2413362489 countsByYear W24133624892020 @default.
- W2413362489 crossrefType "journal-article" @default.
- W2413362489 hasAuthorship W2413362489A5004798262 @default.
- W2413362489 hasAuthorship W2413362489A5049603767 @default.
- W2413362489 hasAuthorship W2413362489A5077249193 @default.
- W2413362489 hasAuthorship W2413362489A5084720605 @default.
- W2413362489 hasConcept C147483822 @default.
- W2413362489 hasConcept C159047783 @default.
- W2413362489 hasConcept C159654299 @default.
- W2413362489 hasConcept C180032290 @default.
- W2413362489 hasConcept C203014093 @default.
- W2413362489 hasConcept C2522874641 @default.
- W2413362489 hasConcept C2776185481 @default.
- W2413362489 hasConcept C2778116200 @default.
- W2413362489 hasConcept C2778706330 @default.
- W2413362489 hasConcept C45189115 @default.
- W2413362489 hasConcept C83455156 @default.
- W2413362489 hasConcept C86803240 @default.
- W2413362489 hasConceptScore W2413362489C147483822 @default.
- W2413362489 hasConceptScore W2413362489C159047783 @default.
- W2413362489 hasConceptScore W2413362489C159654299 @default.
- W2413362489 hasConceptScore W2413362489C180032290 @default.
- W2413362489 hasConceptScore W2413362489C203014093 @default.
- W2413362489 hasConceptScore W2413362489C2522874641 @default.
- W2413362489 hasConceptScore W2413362489C2776185481 @default.
- W2413362489 hasConceptScore W2413362489C2778116200 @default.
- W2413362489 hasConceptScore W2413362489C2778706330 @default.
- W2413362489 hasConceptScore W2413362489C45189115 @default.
- W2413362489 hasConceptScore W2413362489C83455156 @default.
- W2413362489 hasConceptScore W2413362489C86803240 @default.
- W2413362489 hasLocation W24133624891 @default.
- W2413362489 hasLocation W24133624892 @default.
- W2413362489 hasOpenAccess W2413362489 @default.
- W2413362489 hasPrimaryLocation W24133624891 @default.
- W2413362489 hasRelatedWork W158876237 @default.
- W2413362489 hasRelatedWork W1897020130 @default.
- W2413362489 hasRelatedWork W1993524362 @default.
- W2413362489 hasRelatedWork W1997977032 @default.
- W2413362489 hasRelatedWork W2026902070 @default.
- W2413362489 hasRelatedWork W2086202672 @default.
- W2413362489 hasRelatedWork W2138310738 @default.
- W2413362489 hasRelatedWork W2156590770 @default.
- W2413362489 hasRelatedWork W2166584590 @default.
- W2413362489 hasRelatedWork W2290258043 @default.
- W2413362489 hasRelatedWork W2290836584 @default.
- W2413362489 hasRelatedWork W2313567814 @default.
- W2413362489 hasRelatedWork W2341894738 @default.
- W2413362489 hasRelatedWork W2402690733 @default.
- W2413362489 hasRelatedWork W2417558176 @default.
- W2413362489 hasRelatedWork W2510022929 @default.
- W2413362489 hasRelatedWork W2586594610 @default.
- W2413362489 hasRelatedWork W2738011106 @default.
- W2413362489 hasRelatedWork W3034438089 @default.
- W2413362489 hasRelatedWork W2091157800 @default.
- W2413362489 isParatext "false" @default.
- W2413362489 isRetracted "false" @default.
- W2413362489 magId "2413362489" @default.
- W2413362489 workType "article" @default.