Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413368401> ?p ?o ?g. }
- W2413368401 abstract "Bacterial cellulose is a strong and ultrapure form of cellulose produced naturally by several species of the Acetobacteraceae Its high strength, purity, and biocompatibility make it of great interest to materials science; however, precise control of its biosynthesis has remained a challenge for biotechnology. Here we isolate a strain of Komagataeibacter rhaeticus (K. rhaeticus iGEM) that can produce cellulose at high yields, grow in low-nitrogen conditions, and is highly resistant to toxic chemicals. We achieved external control over its bacterial cellulose production through development of a modular genetic toolkit that enables rational reprogramming of the cell. To further its use as an organism for biotechnology, we sequenced its genome and demonstrate genetic circuits that enable functionalization and patterning of heterologous gene expression within the cellulose matrix. This work lays the foundations for using genetic engineering to produce cellulose-based materials, with numerous applications in basic science, materials engineering, and biotechnology." @default.
- W2413368401 created "2016-06-24" @default.
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- W2413368401 date "2016-05-31" @default.
- W2413368401 modified "2023-10-14" @default.
- W2413368401 title "Engineering control of bacterial cellulose production using a genetic toolkit and a new cellulose-producing strain" @default.
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- W2413368401 doi "https://doi.org/10.1073/pnas.1522985113" @default.
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