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- W2413376028 abstract "The effects of gemfibrozil on apolipoproteins C II and C III (apo C II, C III) were observed in 20 NIDDM hyperlipidemic patients. All of the patients continued their anti-diabetic treatment, gemfibrozil 900 mg/day for 4 weeks. The results revealed no significant change in fasting plasma glucose (FPG) and HbA1 before and after the study. But after the treatment with gemfibrozil, the following parameters changed significantly: total cholesterol (TC) decreased by 18.64% (P less than 0.01), total triglyceride (TG) decreased by 65.05% (P less than 0.001), VLDL-C decreased by 63.19% (P less than 0.001), HDL-C increased by 44.23% (P less than 0.001), apo C III decreased by 31.38% (P less than 0.02), and the ratio of apo C III/C II reduced by 35.49% (P less than 0.01). These findings suggest that gemfibrozil has excellent effect on decreasing apo C III and the ratio of apo C III/C II, thus facilitates the metabolism of chylomicron and decreases TG level in hyperlipidemic diabetic patients." @default.
- W2413376028 created "2016-06-24" @default.
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- W2413376028 date "1991-09-01" @default.
- W2413376028 modified "2023-10-16" @default.
- W2413376028 title "[The effect of gemfibrozil on serum apo C II and C III in diabetic hyperlipidemia]." @default.
- W2413376028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1814823" @default.
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