Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413393437> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2413393437 endingPage "21" @default.
- W2413393437 startingPage "215" @default.
- W2413393437 abstract "We examined the mechanisms of disturbed T-lymphocyte function that occurred during Schistosoma japonicum infection of BALB/c mice from the viewpoint of the interleukin cascade reaction. Each point of the interleukin cascade reaction was examined. First, IL-1 production by adherent peritoneal or spleen cells, as a source of macrophages, was normal or rather enhanced during the infection, the values being 100-180% of the control. Secondly, proliferative response to exogenous IL-1 of thymocytes from S. japonicum-infected mice progressively decreased during 3-7 weeks of infection. Thirdly, IL-2 production of S. japonicum-infected mice was significantly inhibited, even at 2 weeks of infection, and the activity was 10-20% of the control at 5-8 weeks of infection. Diminished IL-2 production was not caused by suppressive factors, such as PGE2 or suppressor macrophages, or a decrease in the number of IL-2 producing T cells. Finally, the response to exogenous IL-2 in S. japonicum-infected mice was suppressed markedly by 4 weeks of infection, and the responsiveness was reduced to 20% of the control at 8 weeks of infection. The mechanisms of disturbances in T-cell functions in S. japonicum-infected mice are discussed." @default.
- W2413393437 created "2016-06-24" @default.
- W2413393437 creator A5011998620 @default.
- W2413393437 creator A5018718158 @default.
- W2413393437 creator A5037153149 @default.
- W2413393437 date "1987-10-01" @default.
- W2413393437 modified "2023-10-18" @default.
- W2413393437 title "Studies on the immunological disturbance in murine schistosomiasis japonica from the viewpoint of the interleukin cascade reaction." @default.
- W2413393437 cites W1489113633 @default.
- W2413393437 cites W1504952571 @default.
- W2413393437 cites W1506157243 @default.
- W2413393437 cites W1506916331 @default.
- W2413393437 cites W1516832233 @default.
- W2413393437 cites W1518181528 @default.
- W2413393437 cites W1550447653 @default.
- W2413393437 cites W1599996543 @default.
- W2413393437 cites W1666056236 @default.
- W2413393437 cites W1904441195 @default.
- W2413393437 cites W1971661892 @default.
- W2413393437 cites W2006091217 @default.
- W2413393437 cites W2056796503 @default.
- W2413393437 cites W2071412606 @default.
- W2413393437 cites W2075616595 @default.
- W2413393437 cites W2084093106 @default.
- W2413393437 cites W2146561639 @default.
- W2413393437 cites W2339495317 @default.
- W2413393437 cites W2413207217 @default.
- W2413393437 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1453989" @default.
- W2413393437 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3119470" @default.
- W2413393437 hasPublicationYear "1987" @default.
- W2413393437 type Work @default.
- W2413393437 sameAs 2413393437 @default.
- W2413393437 citedByCount "7" @default.
- W2413393437 countsByYear W24133934372014 @default.
- W2413393437 crossrefType "journal-article" @default.
- W2413393437 hasAuthorship W2413393437A5011998620 @default.
- W2413393437 hasAuthorship W2413393437A5018718158 @default.
- W2413393437 hasAuthorship W2413393437A5037153149 @default.
- W2413393437 hasConcept C165901193 @default.
- W2413393437 hasConcept C203014093 @default.
- W2413393437 hasConcept C2776225656 @default.
- W2413393437 hasConcept C2777123769 @default.
- W2413393437 hasConcept C2777371288 @default.
- W2413393437 hasConcept C2777761686 @default.
- W2413393437 hasConcept C2778690821 @default.
- W2413393437 hasConcept C2780931953 @default.
- W2413393437 hasConcept C2909744060 @default.
- W2413393437 hasConcept C86803240 @default.
- W2413393437 hasConceptScore W2413393437C165901193 @default.
- W2413393437 hasConceptScore W2413393437C203014093 @default.
- W2413393437 hasConceptScore W2413393437C2776225656 @default.
- W2413393437 hasConceptScore W2413393437C2777123769 @default.
- W2413393437 hasConceptScore W2413393437C2777371288 @default.
- W2413393437 hasConceptScore W2413393437C2777761686 @default.
- W2413393437 hasConceptScore W2413393437C2778690821 @default.
- W2413393437 hasConceptScore W2413393437C2780931953 @default.
- W2413393437 hasConceptScore W2413393437C2909744060 @default.
- W2413393437 hasConceptScore W2413393437C86803240 @default.
- W2413393437 hasIssue "2" @default.
- W2413393437 hasLocation W24133934371 @default.
- W2413393437 hasOpenAccess W2413393437 @default.
- W2413393437 hasPrimaryLocation W24133934371 @default.
- W2413393437 hasRelatedWork W1985432924 @default.
- W2413393437 hasRelatedWork W2005332596 @default.
- W2413393437 hasRelatedWork W2028527941 @default.
- W2413393437 hasRelatedWork W2140094212 @default.
- W2413393437 hasRelatedWork W2339495317 @default.
- W2413393437 hasRelatedWork W2364842159 @default.
- W2413393437 hasRelatedWork W2367823740 @default.
- W2413393437 hasRelatedWork W2413393437 @default.
- W2413393437 hasRelatedWork W2433271000 @default.
- W2413393437 hasRelatedWork W571219943 @default.
- W2413393437 hasVolume "62" @default.
- W2413393437 isParatext "false" @default.
- W2413393437 isRetracted "false" @default.
- W2413393437 magId "2413393437" @default.
- W2413393437 workType "article" @default.