FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413405136> ?p ?o ?g. }

• W2413405136 abstract "BackgroundPreclinical studies suggest that the neuropeptide oxytocin reduces food intake and body weight, but only a few clinical studies have investigated the translatability of these findings in humans. The present study investigated the safety and efficacy of oxytocin nasal spray in patients affected by binge eating disorder and obesity.Methods Seventeen outpatients affected by binge eating disorder and obesity participated in a 8 week double-blind trial and received oxytocin (n=8; 24 IU, four times a day, 20 min before each of three meals and before going to bed) or placebo (n=9) with an energy-restricted diet. Primary outcomes included adverse events and the number of binge eating episodes per week. Secondary measures included body weight, BMI, severity of BED, craving for food, quality of sleep, quality of life, anxiety, and depressive symptoms.Results One patient of oxytocin group discontinued prematurely the trial before the first post-randomization efficacy measure. Among the other 16 participants, 13 (81.2%) completed the trial, and 3 (18.8%) discontinued [3 in the oxytocin group; 0 in the placebo group (p=0.0625, Fisher’s exact test)]. No significant difference between groups was found in any outcome evaluated. Patients of the placebo group performed slightly better than patients of the oxytocin group in some secondary outcomes, but these differences were not significant.Conclusion Oxytocin nasal spray resulted to be safe, including in women of childbearing age but did not significantly reduce the number of binge eating episodes per week in outpatients affected by binge eating disorder and obesity. These findings are discussed in light of the human oxytocin literature." @default.
• W2413405136 created "2016-06-24" @default.
• W2413405136 creator A5005751676 @default.
• W2413405136 creator A5023937746 @default.
• W2413405136 creator A5024422484 @default.
• W2413405136 creator A5028749118 @default.
• W2413405136 creator A5030721300 @default.
• W2413405136 creator A5037725529 @default.
• W2413405136 creator A5053007974 @default.
• W2413405136 creator A5063547086 @default.
• W2413405136 creator A5075845304 @default.
• W2413405136 creator A5091119332 @default.
• W2413405136 date "2016-01-01" @default.
• W2413405136 modified "2023-09-24" @default.
• W2413405136 title "Oxytocin Nasal Spray in the Treatment of Binge Eating Disorder and Obesity: A Pilot, Randomized, Double-Blind Trial" @default.
• W2413405136 cites W1532235063 @default.
• W2413405136 cites W1555182331 @default.
• W2413405136 cites W1567805217 @default.
• W2413405136 cites W1815206541 @default.
• W2413405136 cites W1913651286 @default.
• W2413405136 cites W1993305928 @default.
• W2413405136 cites W2027489786 @default.
• W2413405136 cites W2032783309 @default.
• W2413405136 cites W2034407748 @default.
• W2413405136 cites W2043676928 @default.
• W2413405136 cites W2046975053 @default.
• W2413405136 cites W2051346624 @default.
• W2413405136 cites W2055559081 @default.
• W2413405136 cites W2064832639 @default.
• W2413405136 cites W2068155003 @default.
• W2413405136 cites W2071470362 @default.
• W2413405136 cites W2072083924 @default.
• W2413405136 cites W2072500831 @default.
• W2413405136 cites W2076652575 @default.
• W2413405136 cites W2078605997 @default.
• W2413405136 cites W2080796480 @default.
• W2413405136 cites W2086564524 @default.
• W2413405136 cites W2102820596 @default.
• W2413405136 cites W2109173669 @default.
• W2413405136 cites W2114229031 @default.
• W2413405136 cites W2126391111 @default.
• W2413405136 cites W2129575907 @default.
• W2413405136 cites W2138122742 @default.
• W2413405136 cites W2139788240 @default.
• W2413405136 cites W2149248642 @default.
• W2413405136 cites W2149636654 @default.
• W2413405136 cites W2156869908 @default.
• W2413405136 cites W2166166639 @default.
• W2413405136 cites W2167182003 @default.
• W2413405136 cites W2169660513 @default.
• W2413405136 cites W2170332928 @default.
• W2413405136 cites W2172151487 @default.
• W2413405136 cites W2194605942 @default.
• W2413405136 cites W2200366053 @default.
• W2413405136 cites W2202540184 @default.
• W2413405136 cites W2219123932 @default.
• W2413405136 cites W2274519307 @default.
• W2413405136 cites W812470321 @default.
• W2413405136 doi "https://doi.org/10.4172/2167-065x.1000155" @default.
• W2413405136 hasPublicationYear "2016" @default.
• W2413405136 type Work @default.
• W2413405136 sameAs 2413405136 @default.
• W2413405136 citedByCount "7" @default.
• W2413405136 countsByYear W24134051362016 @default.
• W2413405136 countsByYear W24134051362018 @default.
• W2413405136 countsByYear W24134051362021 @default.
• W2413405136 crossrefType "journal-article" @default.
• W2413405136 hasAuthorship W2413405136A5005751676 @default.
• W2413405136 hasAuthorship W2413405136A5023937746 @default.
• W2413405136 hasAuthorship W2413405136A5024422484 @default.
• W2413405136 hasAuthorship W2413405136A5028749118 @default.
• W2413405136 hasAuthorship W2413405136A5030721300 @default.
• W2413405136 hasAuthorship W2413405136A5037725529 @default.
• W2413405136 hasAuthorship W2413405136A5053007974 @default.
• W2413405136 hasAuthorship W2413405136A5063547086 @default.
• W2413405136 hasAuthorship W2413405136A5075845304 @default.
• W2413405136 hasAuthorship W2413405136A5091119332 @default.
• W2413405136 hasBestOaLocation W24134051361 @default.
• W2413405136 hasConcept C118552586 @default.
• W2413405136 hasConcept C126322002 @default.
• W2413405136 hasConcept C131872663 @default.
• W2413405136 hasConcept C142724271 @default.
• W2413405136 hasConcept C168563851 @default.
• W2413405136 hasConcept C204787440 @default.
• W2413405136 hasConcept C27081682 @default.
• W2413405136 hasConcept C2776176026 @default.
• W2413405136 hasConcept C2776394216 @default.
• W2413405136 hasConcept C2777556793 @default.
• W2413405136 hasConcept C2778202721 @default.
• W2413405136 hasConcept C2780973058 @default.
• W2413405136 hasConcept C2781426410 @default.
• W2413405136 hasConcept C2991744798 @default.
• W2413405136 hasConcept C42407357 @default.
• W2413405136 hasConcept C511355011 @default.
• W2413405136 hasConcept C71924100 @default.
• W2413405136 hasConcept C85663871 @default.
• W2413405136 hasConcept C98274493 @default.
• W2413405136 hasConceptScore W2413405136C118552586 @default.
• W2413405136 hasConceptScore W2413405136C126322002 @default.
• W2413405136 hasConceptScore W2413405136C131872663 @default.

• next