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• W2413441665 abstract "Expressive dysphasia and mutism are common clinical features in children and adults with N-methyl-d-aspartate receptor antibodies (NMDAR-Ab) encephalitis, and are likely to result from NMDAR hypofunction. A prodromal loss of social and communication skills can typify that of an autistic regression, particularly when presenting under the age of 3 years. Here we describe two toddlers who presented with developmental regression, particularly of their social communication skills, mimicking an autistic regression, who were found to have NMDAR-Ab in the serum and cerebrospinal fluid. Although both patients had some other neurological features, they were subtle, which resulted in delayed diagnosis of NMDAR-Ab encephalitis. Importantly, immunotherapy was beneficial in both patients, with significant improvement of their language skills and behaviour." @default.
• W2413441665 created "2016-06-24" @default.
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• W2413441665 date "2016-06-03" @default.
• W2413441665 modified "2023-10-17" @default.
• W2413441665 title "<i>N</i>-methyl-<scp>d</scp>-aspartate (NMDA) receptor antibodies encephalitis mimicking an autistic regression" @default.
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• W2413441665 doi "https://doi.org/10.1111/dmcn.13169" @default.
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