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- W2413441720 abstract "Not only are some anti-endothelial cell antibodies (AECA) directed to thus far unidentified cell membrane structures, but some ot them recognize planted antigens and possibly ligand-receptor complexes. The functional heterogeneity of AECA is widely acknowledged: part of them activate the complement, mediate antibody-dependent cell cytotoxicity of trigger the production of tissue procoagulant factor. It has also recently been established that a proportion of AECA have the capacity to induce apoptosis of their target cells. In fact, the most direct demonstration of the pathogenicity of AECA is the autoantibody-induced murine model of vasculitis." @default.
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- W2413441720 date "2003-02-27" @default.
- W2413441720 modified "2023-09-28" @default.
- W2413441720 title "Anti-endothelial cell reactivity, the unresolved enigma." @default.
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