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- W2413460510 abstract "Thirty years after their introduction neuroleptics experience a high rate of failure and intolerance in long-standing serious cases. The contra-indications are concentrated in hospital services due to their associated organic pathology. The clinician is often at a loss in these cases. Benzodiazepines on their own are often insufficient, but well tolerated. Sodium Valproate, aside from its anti-comitial activity, has already proven to be active in the treatment and the prevention of manic episode. Pharmaco-kinetic and pharmaco-dynamic arguments favour a synergic action for Sodium Valproate and Diazepam. This association has been prescribed in fourteen cases of failure, intolerance or contra-indication of neuroleptics in chronic psychotics. Tolerance has been perfect and eight good stable results have been obtained. This association merits study and test in the conditions described." @default.
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- W2413460510 date "1988-04-01" @default.
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- W2413460510 title "[A valproic acid-diazepam combination as an alternative to neuroleptic treatment]." @default.
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