Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413499713> ?p ?o ?g. }
- W2413499713 endingPage "640" @default.
- W2413499713 startingPage "631" @default.
- W2413499713 abstract "Combining a tissue engineering scaffold made of a load-bearing polymer with a hydrogel represents a powerful approach to enhancing the functionalities of the resulting biphasic construct, such as its mechanical properties or ability to support cellular colonization. This research activity was aimed at the development of biphasic scaffolds through the combination of an additively manufactured poly(epsilon-caprolactone) (PCL) fiber construct and a chitosan/poly(gamma-glutamic acid) polyelectrolyte complex hydrogel. By investigating a set of layered structures made of PCL or PCL/hydroxyapatite composite, biphasic scaffold prototypes with good integration of the two phases at the macroscale andmicroscale were developed. The biphasic constructs were able to absorb cell culturemedium up to 10-fold of their weight, and the combination of the two phases had a significant influence on compressive mechanical properties compared with hydrogel or PCL scaffold alone. In addition, due to the presence of chitosan in the hydrogel phase, biphasic scaffolds exerted a broad-spectrum antibacterial activity. The developed biphasic systems appear well suited for application in periodontal bone regenerative approaches in which a biodegradable porous structure providing mechanical stability and a hydrogel phase functioning as absorbing depot of endogenous proteins are simultaneously required. (C) 2016 Society of Chemical Industry" @default.
- W2413499713 created "2016-06-24" @default.
- W2413499713 creator A5003237370 @default.
- W2413499713 creator A5007604530 @default.
- W2413499713 creator A5029516978 @default.
- W2413499713 creator A5031085787 @default.
- W2413499713 creator A5047553525 @default.
- W2413499713 creator A5066705302 @default.
- W2413499713 creator A5083864939 @default.
- W2413499713 date "2016-04-01" @default.
- W2413499713 modified "2023-09-25" @default.
- W2413499713 title "Integrated three-dimensional fiber/hydrogel biphasic scaffolds for periodontal bone tissue engineering" @default.
- W2413499713 cites W1543911216 @default.
- W2413499713 cites W160104111 @default.
- W2413499713 cites W1864530748 @default.
- W2413499713 cites W1964070906 @default.
- W2413499713 cites W1965299016 @default.
- W2413499713 cites W1972446401 @default.
- W2413499713 cites W1979296106 @default.
- W2413499713 cites W1979736123 @default.
- W2413499713 cites W1982416317 @default.
- W2413499713 cites W1984418916 @default.
- W2413499713 cites W2000957726 @default.
- W2413499713 cites W2004401292 @default.
- W2413499713 cites W2007055685 @default.
- W2413499713 cites W2016367750 @default.
- W2413499713 cites W2023758332 @default.
- W2413499713 cites W2027885271 @default.
- W2413499713 cites W2032032896 @default.
- W2413499713 cites W2032357629 @default.
- W2413499713 cites W2032883153 @default.
- W2413499713 cites W2033690944 @default.
- W2413499713 cites W2038987199 @default.
- W2413499713 cites W2041537584 @default.
- W2413499713 cites W2050972482 @default.
- W2413499713 cites W2053585356 @default.
- W2413499713 cites W2055845286 @default.
- W2413499713 cites W2059608826 @default.
- W2413499713 cites W2060550596 @default.
- W2413499713 cites W2061796957 @default.
- W2413499713 cites W2063512506 @default.
- W2413499713 cites W2069025518 @default.
- W2413499713 cites W2069367419 @default.
- W2413499713 cites W2074767961 @default.
- W2413499713 cites W2076605676 @default.
- W2413499713 cites W2084745162 @default.
- W2413499713 cites W2085096967 @default.
- W2413499713 cites W2086746243 @default.
- W2413499713 cites W2087331036 @default.
- W2413499713 cites W2088817736 @default.
- W2413499713 cites W2094676832 @default.
- W2413499713 cites W2102876653 @default.
- W2413499713 cites W2109970288 @default.
- W2413499713 cites W2110902502 @default.
- W2413499713 cites W2111717021 @default.
- W2413499713 cites W2116764640 @default.
- W2413499713 cites W2117112486 @default.
- W2413499713 cites W2129263785 @default.
- W2413499713 cites W2131945662 @default.
- W2413499713 cites W2133142920 @default.
- W2413499713 cites W2133683725 @default.
- W2413499713 cites W2141686927 @default.
- W2413499713 cites W2142852513 @default.
- W2413499713 cites W2146781520 @default.
- W2413499713 cites W2147158757 @default.
- W2413499713 cites W2153320120 @default.
- W2413499713 cites W2156692525 @default.
- W2413499713 cites W2166218291 @default.
- W2413499713 cites W2259970802 @default.
- W2413499713 cites W2337509950 @default.
- W2413499713 cites W2478002580 @default.
- W2413499713 cites W4210956735 @default.
- W2413499713 cites W4244523227 @default.
- W2413499713 cites W782548064 @default.
- W2413499713 doi "https://doi.org/10.1002/pi.5101" @default.
- W2413499713 hasPublicationYear "2016" @default.
- W2413499713 type Work @default.
- W2413499713 sameAs 2413499713 @default.
- W2413499713 citedByCount "35" @default.
- W2413499713 countsByYear W24134997132016 @default.
- W2413499713 countsByYear W24134997132017 @default.
- W2413499713 countsByYear W24134997132018 @default.
- W2413499713 countsByYear W24134997132019 @default.
- W2413499713 countsByYear W24134997132020 @default.
- W2413499713 countsByYear W24134997132021 @default.
- W2413499713 countsByYear W24134997132022 @default.
- W2413499713 crossrefType "journal-article" @default.
- W2413499713 hasAuthorship W2413499713A5003237370 @default.
- W2413499713 hasAuthorship W2413499713A5007604530 @default.
- W2413499713 hasAuthorship W2413499713A5029516978 @default.
- W2413499713 hasAuthorship W2413499713A5031085787 @default.
- W2413499713 hasAuthorship W2413499713A5047553525 @default.
- W2413499713 hasAuthorship W2413499713A5066705302 @default.
- W2413499713 hasAuthorship W2413499713A5083864939 @default.
- W2413499713 hasBestOaLocation W24134997132 @default.
- W2413499713 hasConcept C105702510 @default.
- W2413499713 hasConcept C127413603 @default.
- W2413499713 hasConcept C136229726 @default.