FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413587420> ?p ?o ?g. }

• W2413587420 endingPage "38" @default.
• W2413587420 startingPage "27" @default.
• W2413587420 abstract "OBJECTIVE: Patients with severe neurological injury, such as quadriplegics, might benefit greatly from a brain-machine interface that uses neuronal activity from motor centers to control a neuroprosthetic device. Here, we report an implementation of this strategy in the human intraoperative setting to assess the feasibility of using neurons in subcortical motor areas to drive a human brain-machine interface. METHODS: Acute ensemble recordings from subthalamic nucleus and thalamic motor areas (ventralis oralis posterior [VOP]/ventralis intermediate nucleus [VIM]) were obtained in 11 awake patients during deep brain stimulator surgery by use of a 32-microwire array. During extracellular neuronal recordings, patients simultaneously performed a visual feedback hand-gripping force task. Offline analysis was then used to explore the relationship between neuronal modulation and gripping force. RESULTS: Individual neurons (n = 28 VOP/VIM, n = 119 subthalamic nucleus) demonstrated a variety of modulation responses both before and after onset of changes in gripping force of the contralateral hand. Overall, 61% of subthalamic nucleus neurons and 81% of VOP/VIM neurons modulated with gripping force. Remarkably, ensembles of 3 to 55 simultaneously recorded neurons were sufficiently information-rich to predict gripping force during 30-second test periods with considerable accuracy (up to R = 0.82, R2 = 0.68) after short training periods. Longer training periods and larger neuronal ensembles were associated with improved predictive accuracy. CONCLUSION: This initial feasibility study bridges the gap between the nonhuman primate laboratory and the human intraoperative setting to suggest that neuronal ensembles from human subcortical motor regions may be able to provide informative control signals to a future brain-machine interface." @default.
• W2413587420 created "2016-06-24" @default.
• W2413587420 creator A5016475757 @default.
• W2413587420 creator A5024864142 @default.
• W2413587420 creator A5042829515 @default.
• W2413587420 creator A5048735359 @default.
• W2413587420 date "2004-07-01" @default.
• W2413587420 modified "2023-10-10" @default.
• W2413587420 title "Ensemble Recordings Of Human Subcortical Neurons as a Source Of Motor Control Signals For a Brain-Machine Interface" @default.
• W2413587420 cites W1543237449 @default.
• W2413587420 cites W1596990491 @default.
• W2413587420 cites W1879986663 @default.
• W2413587420 cites W1949922239 @default.
• W2413587420 cites W1967055605 @default.
• W2413587420 cites W1977278164 @default.
• W2413587420 cites W1979729980 @default.
• W2413587420 cites W1987035135 @default.
• W2413587420 cites W1988918035 @default.
• W2413587420 cites W1989605251 @default.
• W2413587420 cites W2000622391 @default.
• W2413587420 cites W2003552158 @default.
• W2413587420 cites W2003766373 @default.
• W2413587420 cites W2007030844 @default.
• W2413587420 cites W2012159882 @default.
• W2413587420 cites W2020769260 @default.
• W2413587420 cites W2023295798 @default.
• W2413587420 cites W2024912092 @default.
• W2413587420 cites W2030396712 @default.
• W2413587420 cites W2033067344 @default.
• W2413587420 cites W2038804781 @default.
• W2413587420 cites W2041248708 @default.
• W2413587420 cites W2041364673 @default.
• W2413587420 cites W2043721804 @default.
• W2413587420 cites W2050541834 @default.
• W2413587420 cites W2053011627 @default.
• W2413587420 cites W2056445269 @default.
• W2413587420 cites W2059376965 @default.
• W2413587420 cites W2063327478 @default.
• W2413587420 cites W2085753568 @default.
• W2413587420 cites W2095504054 @default.
• W2413587420 cites W2100959730 @default.
• W2413587420 cites W2106006415 @default.
• W2413587420 cites W2108157570 @default.
• W2413587420 cites W2150499782 @default.
• W2413587420 cites W2155888616 @default.
• W2413587420 cites W2156598590 @default.
• W2413587420 cites W2161457168 @default.
• W2413587420 cites W2163503262 @default.
• W2413587420 cites W2288785867 @default.
• W2413587420 cites W2305277766 @default.
• W2413587420 cites W2332756313 @default.
• W2413587420 cites W2573365936 @default.
• W2413587420 cites W4253453051 @default.
• W2413587420 cites W4321059940 @default.
• W2413587420 doi "https://doi.org/10.1227/01.neu.0000126872.23715.e5" @default.
• W2413587420 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15214971" @default.
• W2413587420 hasPublicationYear "2004" @default.
• W2413587420 type Work @default.
• W2413587420 sameAs 2413587420 @default.
• W2413587420 citedByCount "170" @default.
• W2413587420 countsByYear W24135874202012 @default.
• W2413587420 countsByYear W24135874202013 @default.
• W2413587420 countsByYear W24135874202014 @default.
• W2413587420 countsByYear W24135874202015 @default.
• W2413587420 countsByYear W24135874202016 @default.
• W2413587420 countsByYear W24135874202017 @default.
• W2413587420 countsByYear W24135874202018 @default.
• W2413587420 countsByYear W24135874202019 @default.
• W2413587420 countsByYear W24135874202020 @default.
• W2413587420 countsByYear W24135874202021 @default.
• W2413587420 countsByYear W24135874202022 @default.
• W2413587420 countsByYear W24135874202023 @default.
• W2413587420 crossrefType "journal-article" @default.
• W2413587420 hasAuthorship W2413587420A5016475757 @default.
• W2413587420 hasAuthorship W2413587420A5024864142 @default.
• W2413587420 hasAuthorship W2413587420A5042829515 @default.
• W2413587420 hasAuthorship W2413587420A5048735359 @default.
• W2413587420 hasConcept C137813230 @default.
• W2413587420 hasConcept C142724271 @default.
• W2413587420 hasConcept C15744967 @default.
• W2413587420 hasConcept C169760540 @default.
• W2413587420 hasConcept C173201364 @default.
• W2413587420 hasConcept C185263204 @default.
• W2413587420 hasConcept C2777319143 @default.
• W2413587420 hasConcept C2777670902 @default.
• W2413587420 hasConcept C2778542668 @default.
• W2413587420 hasConcept C2779134260 @default.
• W2413587420 hasConcept C2779734285 @default.
• W2413587420 hasConcept C2780723820 @default.
• W2413587420 hasConcept C522805319 @default.
• W2413587420 hasConcept C71924100 @default.
• W2413587420 hasConcept C74254510 @default.
• W2413587420 hasConceptScore W2413587420C137813230 @default.
• W2413587420 hasConceptScore W2413587420C142724271 @default.
• W2413587420 hasConceptScore W2413587420C15744967 @default.
• W2413587420 hasConceptScore W2413587420C169760540 @default.
• W2413587420 hasConceptScore W2413587420C173201364 @default.
• W2413587420 hasConceptScore W2413587420C185263204 @default.

• next