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- W2413666592 abstract "Synovia and synovial fluid proteinases were determined in 21 patients with rheumatoid arthritis who were using different kinds of antirheumatic medications. Significantly lower cathepsin B1-like proteinase activity (only 10% of control) was found in the synovial fluid of patients with chloroquine treatment, and significantly lower neutral trypsin-substrate hydrolysing proteinase activity (about 30% of control) was found in the synovia of patients with phenylbutazone treatment. No significant differences were found with other medications: gold, indomethacin, cortisone, acetylsalicyclic acid. No definitive correlations between disease activity parameters and proteinase activities could be found." @default.
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- W2413666592 date "1978-09-01" @default.
- W2413666592 modified "2023-09-23" @default.
- W2413666592 title "Effect of antirheumatic drugs on proteinases in synovia of patients with rheumatoid arthritis." @default.
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