FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413667076> ?p ?o ?g. }

• W2413667076 endingPage "7" @default.
• W2413667076 startingPage "973" @default.
• W2413667076 abstract "The action of the anti-asthmatic drug sodium cromoglycate (SCG) on airway inflammation remains uncertain. Using Evans blue dye as a maker of plasma leakage, we studied the effect of SCG on neurogenic vascular extravasation evoked by hypertonic saline (HTS) in the rat trachea. Inhalation of HTS (5-15%) caused a concentration-dependent increase in plasma leakage, but inhaled 0.9% NaCl had no effect. Inhalation of SCG did not affect the baseline level of vascular permeability, but it inhibited the effect of HTS in a dose-dependent manner: plasma extravasation induced by 10% NaCl was significantly reduced by 2 minutes of inhalation of SCG at concentrations of 10 and 50 mg/ml (p < 0.05 and p < 0.01, respectively). SCG (10 mg/ml), also inhibited the changes in microvascular permeability caused by aerosols of substance P (10(-4) M), whereas it did not affect the responses to aerosols of platelet-activating factor (3 x 10(-4) M). A similar dose of SCG did not significantly alter microvascular leakage caused by 5% NaCl. However, phosphoramidon, a selective inhibitor of neutral endopeptidase, potentiated the response to 5% NaCl, an effect that was inhibited by SCG (p < 0.05). These results suggest that SCG inhibits HTS-induced airway vascular permeability, presumably through a tachykinin-antagonist-like property, and that this inhibition is exaggerated when the activity of endogenous neutral endopeptidase is low." @default.
• W2413667076 created "2016-06-24" @default.
• W2413667076 creator A5046225422 @default.
• W2413667076 creator A5049396499 @default.
• W2413667076 creator A5056309692 @default.
• W2413667076 creator A5090316407 @default.
• W2413667076 date "1996-09-01" @default.
• W2413667076 modified "2023-09-23" @default.
• W2413667076 title "[Effect of sodium cromoglycate on airway vascular leakage caused by hypertonic saline in the rat trachea]." @default.
• W2413667076 cites W1411221516 @default.
• W2413667076 cites W1869326453 @default.
• W2413667076 cites W1980037780 @default.
• W2413667076 cites W2012032810 @default.
• W2413667076 cites W2023426963 @default.
• W2413667076 cites W2026540392 @default.
• W2413667076 cites W2035238376 @default.
• W2413667076 cites W2037077008 @default.
• W2413667076 cites W2039959280 @default.
• W2413667076 cites W2042059353 @default.
• W2413667076 cites W2048228896 @default.
• W2413667076 cites W2049452083 @default.
• W2413667076 cites W2064222371 @default.
• W2413667076 cites W2077096101 @default.
• W2413667076 cites W2085061625 @default.
• W2413667076 cites W2116315384 @default.
• W2413667076 cites W2178219371 @default.
• W2413667076 cites W2230473435 @default.
• W2413667076 cites W2285130756 @default.
• W2413667076 cites W38947021 @default.
• W2413667076 cites W1874368752 @default.
• W2413667076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8937140" @default.
• W2413667076 hasPublicationYear "1996" @default.
• W2413667076 type Work @default.
• W2413667076 sameAs 2413667076 @default.
• W2413667076 citedByCount "0" @default.
• W2413667076 crossrefType "journal-article" @default.
• W2413667076 hasAuthorship W2413667076A5046225422 @default.
• W2413667076 hasAuthorship W2413667076A5049396499 @default.
• W2413667076 hasAuthorship W2413667076A5056309692 @default.
• W2413667076 hasAuthorship W2413667076A5090316407 @default.
• W2413667076 hasConcept C104826730 @default.
• W2413667076 hasConcept C113045295 @default.
• W2413667076 hasConcept C117277713 @default.
• W2413667076 hasConcept C126322002 @default.
• W2413667076 hasConcept C134018914 @default.
• W2413667076 hasConcept C144980905 @default.
• W2413667076 hasConcept C170493617 @default.
• W2413667076 hasConcept C181199279 @default.
• W2413667076 hasConcept C185592680 @default.
• W2413667076 hasConcept C203014093 @default.
• W2413667076 hasConcept C2776954882 @default.
• W2413667076 hasConcept C2777397205 @default.
• W2413667076 hasConcept C2777649898 @default.
• W2413667076 hasConcept C2779020240 @default.
• W2413667076 hasConcept C2779540182 @default.
• W2413667076 hasConcept C2780268870 @default.
• W2413667076 hasConcept C3017567848 @default.
• W2413667076 hasConcept C42219234 @default.
• W2413667076 hasConcept C55493867 @default.
• W2413667076 hasConcept C71924100 @default.
• W2413667076 hasConcept C98274493 @default.
• W2413667076 hasConceptScore W2413667076C104826730 @default.
• W2413667076 hasConceptScore W2413667076C113045295 @default.
• W2413667076 hasConceptScore W2413667076C117277713 @default.
• W2413667076 hasConceptScore W2413667076C126322002 @default.
• W2413667076 hasConceptScore W2413667076C134018914 @default.
• W2413667076 hasConceptScore W2413667076C144980905 @default.
• W2413667076 hasConceptScore W2413667076C170493617 @default.
• W2413667076 hasConceptScore W2413667076C181199279 @default.
• W2413667076 hasConceptScore W2413667076C185592680 @default.
• W2413667076 hasConceptScore W2413667076C203014093 @default.
• W2413667076 hasConceptScore W2413667076C2776954882 @default.
• W2413667076 hasConceptScore W2413667076C2777397205 @default.
• W2413667076 hasConceptScore W2413667076C2777649898 @default.
• W2413667076 hasConceptScore W2413667076C2779020240 @default.
• W2413667076 hasConceptScore W2413667076C2779540182 @default.
• W2413667076 hasConceptScore W2413667076C2780268870 @default.
• W2413667076 hasConceptScore W2413667076C3017567848 @default.
• W2413667076 hasConceptScore W2413667076C42219234 @default.
• W2413667076 hasConceptScore W2413667076C55493867 @default.
• W2413667076 hasConceptScore W2413667076C71924100 @default.
• W2413667076 hasConceptScore W2413667076C98274493 @default.
• W2413667076 hasIssue "9" @default.
• W2413667076 hasLocation W24136670761 @default.
• W2413667076 hasOpenAccess W2413667076 @default.
• W2413667076 hasPrimaryLocation W24136670761 @default.
• W2413667076 hasRelatedWork W1984111294 @default.
• W2413667076 hasRelatedWork W1987007184 @default.
• W2413667076 hasRelatedWork W2019304601 @default.
• W2413667076 hasRelatedWork W2237064277 @default.
• W2413667076 hasRelatedWork W2413667076 @default.
• W2413667076 hasRelatedWork W2418654938 @default.
• W2413667076 hasRelatedWork W2427943782 @default.
• W2413667076 hasRelatedWork W1874368752 @default.
• W2413667076 hasRelatedWork W2131472081 @default.
• W2413667076 hasRelatedWork W2187041839 @default.
• W2413667076 hasVolume "34" @default.
• W2413667076 isParatext "false" @default.

• next