Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413750302> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2413750302 endingPage "18" @default.
- W2413750302 startingPage "702" @default.
- W2413750302 abstract "This study examined the wound healing process of rat pulp directly capped with various experimentally developed adhesive resin systems and treated with CO2 laser irradiation. The experimental adhesive resins used in this study were made from Clearfil Mega Bond (MB). The adhesive resin groups were capped with a combination of the following primers and bonding agents: commercially available MB primer (MBP), experimental MB primer containing 2wt% N-methacryloyl 5-aminosalicylic acid (5-NMSA: MP3) and 5wt% 12-methacryloyloxydodecylpyridinium bromide (MDPB: ABP); and commercially available MB bonding agent (MBB), experimental MB bonding agent containing 5wt% and 10wt% hydroxyl-calcium phosphate (hydroxyapatite: MB1, MB2) and 5wt% dicalcium phosphate dihydrate (brushite: MB3) as a reparative dentin-promoter. The combination of the three primers and four bonding agents yielded the 12 adhesive resin groups used in this study. The CO2 laser group was irradiated with a laser and directly capped with MB. The CO2 laser used was an Opelaser 03S II SP, and irradiation conditions were as follows: a power output of 0.5 W, superpulse mode 1, repeat pulse mode (a cycle of 10 msec irradiation and 10 msec interval), defocused beam (approximately distance 20 mm from pulp exposure surface) and an irradiation time of three seconds, with air cooling. The control group was capped with Dycal (DY) and MB. After the direct pulp capping procedures were undertaken, all cavities were restored with Clearfil AP-X resin composite. The rats were sacrificed on the 14th post-operative day. The specimens were alternately stained with Mayer's H & E, Hucker-Conn bacterial stain and the ABC method on TGF-beta1. These stained sections were observed using light microscopy and the following parameters were evaluated: pulp tissue disorganization, inflammatory cell infiltration, reparative dentin formation and bacterial penetration. The results of this study include the following: all experimentally developed bonding agent groups showed reparative dentin formation; whereas, the MBB-capped groups showed very little reparative dentin formation. The descending order regarding the amount of reparative dentin formation was MB2 > MB3 > MB1 >>> MBB, which tended to be dependent on the concentration of the blended reparative dentin-promoter. In terms of the quality of the formed dentin, it was observed that MB1-capped teeth tended to form tubular dentin; whereas, MB2- and MB3-capped teeth formed irregular and osteodentin types of dentin. Among the primers used, the descending order regarding the amount of reparative dentin and tubular type dentin formation was MP3 > MBP > ABP. The descending order of migration of macrophages and leukocytes was ABP > MBP > MP3. The CO2 laser group showed a very irregular fibrous dentin matrix in the vicinity of the denatured and carbonized tissue but definite reparative dentin formation was not observed. The control group showed reparative dentin, which was very thick, compared with the other groups. In all the groups, pulp tissue showed almost normal morphology. Positive staining of TGF-beta1 was only observed slightly in some specimens of all groups. There was no difference in the staining of each group. Based on the results of this study, it was concluded that the combination of MP3 (containing 2wt% 5-NMSA) and MB1 (containing 5wt% hydroxyapatite) was effective in initiating an early repair process after direct pulp capping. CO2 laser irradiation is effective for field control, but a longer observation time will be required to determine findings concerning dentin bridge formation." @default.
- W2413750302 created "2016-06-24" @default.
- W2413750302 creator A5009291154 @default.
- W2413750302 creator A5022702152 @default.
- W2413750302 creator A5043405539 @default.
- W2413750302 creator A5058401861 @default.
- W2413750302 creator A5066948730 @default.
- W2413750302 date "2005-12-31" @default.
- W2413750302 modified "2023-09-29" @default.
- W2413750302 title "Effects of an experimentally developed adhesive resin system and CO2 laser irradiation on direct pulp capping." @default.
- W2413750302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16382593" @default.
- W2413750302 hasPublicationYear "2005" @default.
- W2413750302 type Work @default.
- W2413750302 sameAs 2413750302 @default.
- W2413750302 citedByCount "8" @default.
- W2413750302 countsByYear W24137503022015 @default.
- W2413750302 countsByYear W24137503022016 @default.
- W2413750302 countsByYear W24137503022023 @default.
- W2413750302 crossrefType "journal-article" @default.
- W2413750302 hasAuthorship W2413750302A5009291154 @default.
- W2413750302 hasAuthorship W2413750302A5022702152 @default.
- W2413750302 hasAuthorship W2413750302A5043405539 @default.
- W2413750302 hasAuthorship W2413750302A5058401861 @default.
- W2413750302 hasAuthorship W2413750302A5066948730 @default.
- W2413750302 hasConcept C104779481 @default.
- W2413750302 hasConcept C111337013 @default.
- W2413750302 hasConcept C121332964 @default.
- W2413750302 hasConcept C13965031 @default.
- W2413750302 hasConcept C159096172 @default.
- W2413750302 hasConcept C159985019 @default.
- W2413750302 hasConcept C161312837 @default.
- W2413750302 hasConcept C185544564 @default.
- W2413750302 hasConcept C185592680 @default.
- W2413750302 hasConcept C188442228 @default.
- W2413750302 hasConcept C192562407 @default.
- W2413750302 hasConcept C199343813 @default.
- W2413750302 hasConcept C2778265030 @default.
- W2413750302 hasConcept C2779227376 @default.
- W2413750302 hasConcept C2779263046 @default.
- W2413750302 hasConcept C68928338 @default.
- W2413750302 hasConcept C71924100 @default.
- W2413750302 hasConceptScore W2413750302C104779481 @default.
- W2413750302 hasConceptScore W2413750302C111337013 @default.
- W2413750302 hasConceptScore W2413750302C121332964 @default.
- W2413750302 hasConceptScore W2413750302C13965031 @default.
- W2413750302 hasConceptScore W2413750302C159096172 @default.
- W2413750302 hasConceptScore W2413750302C159985019 @default.
- W2413750302 hasConceptScore W2413750302C161312837 @default.
- W2413750302 hasConceptScore W2413750302C185544564 @default.
- W2413750302 hasConceptScore W2413750302C185592680 @default.
- W2413750302 hasConceptScore W2413750302C188442228 @default.
- W2413750302 hasConceptScore W2413750302C192562407 @default.
- W2413750302 hasConceptScore W2413750302C199343813 @default.
- W2413750302 hasConceptScore W2413750302C2778265030 @default.
- W2413750302 hasConceptScore W2413750302C2779227376 @default.
- W2413750302 hasConceptScore W2413750302C2779263046 @default.
- W2413750302 hasConceptScore W2413750302C68928338 @default.
- W2413750302 hasConceptScore W2413750302C71924100 @default.
- W2413750302 hasIssue "6" @default.
- W2413750302 hasLocation W24137503021 @default.
- W2413750302 hasOpenAccess W2413750302 @default.
- W2413750302 hasPrimaryLocation W24137503021 @default.
- W2413750302 hasRelatedWork W1230658161 @default.
- W2413750302 hasRelatedWork W13678307 @default.
- W2413750302 hasRelatedWork W2000382687 @default.
- W2413750302 hasRelatedWork W2011442116 @default.
- W2413750302 hasRelatedWork W2011977325 @default.
- W2413750302 hasRelatedWork W2012400834 @default.
- W2413750302 hasRelatedWork W2012974227 @default.
- W2413750302 hasRelatedWork W2035944449 @default.
- W2413750302 hasRelatedWork W2074433735 @default.
- W2413750302 hasRelatedWork W2080987493 @default.
- W2413750302 hasRelatedWork W2084720555 @default.
- W2413750302 hasRelatedWork W215859734 @default.
- W2413750302 hasRelatedWork W2280524984 @default.
- W2413750302 hasRelatedWork W2286768362 @default.
- W2413750302 hasRelatedWork W2396783351 @default.
- W2413750302 hasRelatedWork W2400174458 @default.
- W2413750302 hasRelatedWork W2408593291 @default.
- W2413750302 hasRelatedWork W2418605857 @default.
- W2413750302 hasRelatedWork W56941273 @default.
- W2413750302 hasRelatedWork W66933032 @default.
- W2413750302 hasVolume "30" @default.
- W2413750302 isParatext "false" @default.
- W2413750302 isRetracted "false" @default.
- W2413750302 magId "2413750302" @default.
- W2413750302 workType "article" @default.