FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413826048> ?p ?o ?g. }

• W2413826048 abstract "Abstract Freshly isolated hairy cells from the peripheral blood of patients with hairy cell leukemia (HCL) synthesize 3–5-fold greater amounts of cholesterol, lanosterol, and squalene from [1–14C]-acetate than do normal human peripheral blood mononuclear cells under basal conditions of culture (i.e., in the presence of low-density lipoprotein). HCL cells also exhibit an eightfold increase in the activity of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A reductase. These changes cannot be ascribed to increased rates of cellular proliferation in the HCL cells, nor are they a consequence of an increased rate of loss of newly synthesized cholesterol into the culture medium. The increased rate of cholesterol biosynthesis in HCL cells may result in an increase in their total cellular cholesterol content, as well as in an increase in their plasma membrane cholesterol:phospholipid molar ratio. These changes, in turn, are probably responsible for some of the clinical manifestations of this disease." @default.
• W2413826048 created "2016-06-24" @default.
• W2413826048 creator A5039170975 @default.
• W2413826048 creator A5075720529 @default.
• W2413826048 date "1984-03-01" @default.
• W2413826048 modified "2023-09-27" @default.
• W2413826048 title "Increased 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol biosynthesis in freshly isolated hairy cell leukemia cells" @default.
• W2413826048 cites W1589577300 @default.
• W2413826048 cites W1799874541 @default.
• W2413826048 cites W1979827465 @default.
• W2413826048 cites W2025346008 @default.
• W2413826048 cites W2029691030 @default.
• W2413826048 cites W2050124920 @default.
• W2413826048 cites W2110705667 @default.
• W2413826048 cites W2116328518 @default.
• W2413826048 cites W2137138829 @default.
• W2413826048 cites W2146204566 @default.
• W2413826048 cites W2186134888 @default.
• W2413826048 cites W2279344163 @default.
• W2413826048 cites W2396303855 @default.
• W2413826048 cites W2416188886 @default.
• W2413826048 doi "https://doi.org/10.1182/blood.v63.3.690.690" @default.
• W2413826048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6696995" @default.
• W2413826048 hasPublicationYear "1984" @default.
• W2413826048 type Work @default.
• W2413826048 sameAs 2413826048 @default.
• W2413826048 citedByCount "12" @default.
• W2413826048 countsByYear W24138260482013 @default.
• W2413826048 countsByYear W24138260482015 @default.
• W2413826048 countsByYear W24138260482017 @default.
• W2413826048 countsByYear W24138260482019 @default.
• W2413826048 countsByYear W24138260482020 @default.
• W2413826048 crossrefType "journal-article" @default.
• W2413826048 hasAuthorship W2413826048A5039170975 @default.
• W2413826048 hasAuthorship W2413826048A5075720529 @default.
• W2413826048 hasBestOaLocation W24138260481 @default.
• W2413826048 hasConcept C104950815 @default.
• W2413826048 hasConcept C126322002 @default.
• W2413826048 hasConcept C134018914 @default.
• W2413826048 hasConcept C134651460 @default.
• W2413826048 hasConcept C137061746 @default.
• W2413826048 hasConcept C181199279 @default.
• W2413826048 hasConcept C185592680 @default.
• W2413826048 hasConcept C202751555 @default.
• W2413826048 hasConcept C2776703722 @default.
• W2413826048 hasConcept C2777320049 @default.
• W2413826048 hasConcept C2778163477 @default.
• W2413826048 hasConcept C2778718757 @default.
• W2413826048 hasConcept C2778918659 @default.
• W2413826048 hasConcept C2779123261 @default.
• W2413826048 hasConcept C2779969316 @default.
• W2413826048 hasConcept C41625074 @default.
• W2413826048 hasConcept C553450214 @default.
• W2413826048 hasConcept C55493867 @default.
• W2413826048 hasConcept C71924100 @default.
• W2413826048 hasConcept C86803240 @default.
• W2413826048 hasConceptScore W2413826048C104950815 @default.
• W2413826048 hasConceptScore W2413826048C126322002 @default.
• W2413826048 hasConceptScore W2413826048C134018914 @default.
• W2413826048 hasConceptScore W2413826048C134651460 @default.
• W2413826048 hasConceptScore W2413826048C137061746 @default.
• W2413826048 hasConceptScore W2413826048C181199279 @default.
• W2413826048 hasConceptScore W2413826048C185592680 @default.
• W2413826048 hasConceptScore W2413826048C202751555 @default.
• W2413826048 hasConceptScore W2413826048C2776703722 @default.
• W2413826048 hasConceptScore W2413826048C2777320049 @default.
• W2413826048 hasConceptScore W2413826048C2778163477 @default.
• W2413826048 hasConceptScore W2413826048C2778718757 @default.
• W2413826048 hasConceptScore W2413826048C2778918659 @default.
• W2413826048 hasConceptScore W2413826048C2779123261 @default.
• W2413826048 hasConceptScore W2413826048C2779969316 @default.
• W2413826048 hasConceptScore W2413826048C41625074 @default.
• W2413826048 hasConceptScore W2413826048C553450214 @default.
• W2413826048 hasConceptScore W2413826048C55493867 @default.
• W2413826048 hasConceptScore W2413826048C71924100 @default.
• W2413826048 hasConceptScore W2413826048C86803240 @default.
• W2413826048 hasLocation W24138260481 @default.
• W2413826048 hasOpenAccess W2413826048 @default.
• W2413826048 hasPrimaryLocation W24138260481 @default.
• W2413826048 hasRelatedWork W1539901397 @default.
• W2413826048 hasRelatedWork W1541030074 @default.
• W2413826048 hasRelatedWork W1578418346 @default.
• W2413826048 hasRelatedWork W1612390895 @default.
• W2413826048 hasRelatedWork W184483015 @default.
• W2413826048 hasRelatedWork W1878812720 @default.
• W2413826048 hasRelatedWork W1966128598 @default.
• W2413826048 hasRelatedWork W1973596992 @default.
• W2413826048 hasRelatedWork W1978384651 @default.
• W2413826048 hasRelatedWork W1982578825 @default.
• W2413826048 hasRelatedWork W2043903113 @default.
• W2413826048 hasRelatedWork W2071124826 @default.
• W2413826048 hasRelatedWork W2073262272 @default.
• W2413826048 hasRelatedWork W2085137882 @default.
• W2413826048 hasRelatedWork W2100367059 @default.
• W2413826048 hasRelatedWork W2107366352 @default.
• W2413826048 hasRelatedWork W2135366531 @default.
• W2413826048 hasRelatedWork W2285829831 @default.
• W2413826048 hasRelatedWork W2341279355 @default.
• W2413826048 hasRelatedWork W2474574952 @default.
• W2413826048 isParatext "false" @default.

• next