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- W2413846589 abstract "Effector T-cell responses are controlled by complex mechanisms involving various soluble factors and co-stimulatory and co-inhibitory molecules. These inhibitory receptors act as immune checkpoints and are extensively investigated as possible therapeutic targets, such as PD-1 and CTLA-4. Recently TIM-3 is also gaining prominence in tumor and chronic viral infection models as a candidate for immunotherapy in conjunction with other inhibitory receptors. This review discusses the recent findings on the expression of TIM-3 and its ligand in tumor and chronic viral infection." @default.
- W2413846589 created "2016-06-24" @default.
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- W2413846589 date "2014-01-01" @default.
- W2413846589 modified "2023-09-23" @default.
- W2413846589 title "TIM-3, a Possible Target for Immunotherapy in Cancer and Chronic Viral Infections." @default.
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