Matches in SemOpenAlex for { <https://semopenalex.org/work/W2413895909> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2413895909 endingPage "90" @default.
- W2413895909 startingPage "85" @default.
- W2413895909 abstract "Hepatitis B virus infection is responsible of an important number of world morbimortality. This is associated to severe liver outcome such as cirrhosis and hepatocellular carcinoma. Diverse factors influence the severity of liver injury produced by Hepatitis B Virus (HBV): the emergence of HBV mutants unable to secrete e antigen (pre-core mutants), the virus and host genetic heterogenicity and immune system competence. Particularly, the presence of pre-core mutants in chronic carriers is associated a low response to interferon therapy. We present paper is to present evidence as to the presence of these mutants in chronically infected, HBeAg negative patients (HBsAg positive) in Argentina. Viral DNAs were extracted from sera of nine patients, amplified by PCR and characterized by restriction enzyme assay. All of them appear to be pre-core mutants according with serological markers and a very low level of viral DNA detected in serum. Further genetic characterization of one of them by nucleotide sequence analysis of the pre-core region let allowed us to show modifications at codon 15 and 28 both of them previously described for pre-core mutants." @default.
- W2413895909 created "2016-06-24" @default.
- W2413895909 creator A5001739435 @default.
- W2413895909 creator A5006113742 @default.
- W2413895909 creator A5043250186 @default.
- W2413895909 creator A5052349382 @default.
- W2413895909 creator A5056495655 @default.
- W2413895909 creator A5081160721 @default.
- W2413895909 date "1995-01-01" @default.
- W2413895909 modified "2023-09-23" @default.
- W2413895909 title "[Detection and characterization of pre-core mutants of hepatitis B virus (HBV) in chronically infected patients]." @default.
- W2413895909 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8525764" @default.
- W2413895909 hasPublicationYear "1995" @default.
- W2413895909 type Work @default.
- W2413895909 sameAs 2413895909 @default.
- W2413895909 citedByCount "2" @default.
- W2413895909 crossrefType "journal-article" @default.
- W2413895909 hasAuthorship W2413895909A5001739435 @default.
- W2413895909 hasAuthorship W2413895909A5006113742 @default.
- W2413895909 hasAuthorship W2413895909A5043250186 @default.
- W2413895909 hasAuthorship W2413895909A5052349382 @default.
- W2413895909 hasAuthorship W2413895909A5056495655 @default.
- W2413895909 hasAuthorship W2413895909A5081160721 @default.
- W2413895909 hasConcept C104317684 @default.
- W2413895909 hasConcept C143065580 @default.
- W2413895909 hasConcept C159047783 @default.
- W2413895909 hasConcept C159654299 @default.
- W2413895909 hasConcept C203014093 @default.
- W2413895909 hasConcept C2522874641 @default.
- W2413895909 hasConcept C2775940106 @default.
- W2413895909 hasConcept C2777214474 @default.
- W2413895909 hasConcept C2777382497 @default.
- W2413895909 hasConcept C2777410769 @default.
- W2413895909 hasConcept C2778019345 @default.
- W2413895909 hasConcept C2780593183 @default.
- W2413895909 hasConcept C45189115 @default.
- W2413895909 hasConcept C502942594 @default.
- W2413895909 hasConcept C54355233 @default.
- W2413895909 hasConcept C71924100 @default.
- W2413895909 hasConcept C86803240 @default.
- W2413895909 hasConcept C90924648 @default.
- W2413895909 hasConceptScore W2413895909C104317684 @default.
- W2413895909 hasConceptScore W2413895909C143065580 @default.
- W2413895909 hasConceptScore W2413895909C159047783 @default.
- W2413895909 hasConceptScore W2413895909C159654299 @default.
- W2413895909 hasConceptScore W2413895909C203014093 @default.
- W2413895909 hasConceptScore W2413895909C2522874641 @default.
- W2413895909 hasConceptScore W2413895909C2775940106 @default.
- W2413895909 hasConceptScore W2413895909C2777214474 @default.
- W2413895909 hasConceptScore W2413895909C2777382497 @default.
- W2413895909 hasConceptScore W2413895909C2777410769 @default.
- W2413895909 hasConceptScore W2413895909C2778019345 @default.
- W2413895909 hasConceptScore W2413895909C2780593183 @default.
- W2413895909 hasConceptScore W2413895909C45189115 @default.
- W2413895909 hasConceptScore W2413895909C502942594 @default.
- W2413895909 hasConceptScore W2413895909C54355233 @default.
- W2413895909 hasConceptScore W2413895909C71924100 @default.
- W2413895909 hasConceptScore W2413895909C86803240 @default.
- W2413895909 hasConceptScore W2413895909C90924648 @default.
- W2413895909 hasIssue "2" @default.
- W2413895909 hasLocation W24138959091 @default.
- W2413895909 hasOpenAccess W2413895909 @default.
- W2413895909 hasPrimaryLocation W24138959091 @default.
- W2413895909 hasRelatedWork W1590937413 @default.
- W2413895909 hasRelatedWork W1919496130 @default.
- W2413895909 hasRelatedWork W1978794620 @default.
- W2413895909 hasRelatedWork W2067220281 @default.
- W2413895909 hasRelatedWork W2208893463 @default.
- W2413895909 hasRelatedWork W2296786213 @default.
- W2413895909 hasRelatedWork W2418826069 @default.
- W2413895909 hasRelatedWork W3032194499 @default.
- W2413895909 hasRelatedWork W3142514864 @default.
- W2413895909 hasRelatedWork W2107508000 @default.
- W2413895909 hasVolume "25" @default.
- W2413895909 isParatext "false" @default.
- W2413895909 isRetracted "false" @default.
- W2413895909 magId "2413895909" @default.
- W2413895909 workType "article" @default.