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- W2414107035 abstract "To observe the effects of the extract of blackend swallowwort root (EBSR) on neovascularization after partial hepatectomy and explore the corresponding molecules and mechanism of the regulation.Twenty mice were randomly divided into control group and EBSR group. Mice in the two groups were subjected to a one-time resection of part of the left lateral lobe of the liver. The mice in the experimental group were treated with EBSR by intragastric administration at a dose of 50 g/kg, twice per day after operation. During the eight days after the operation, one mouse in each group was sacrificed every day and the left lateral liver lobe was harvested. Immunohistochemistry was used to detect the expressions of vascular endothelial growth factor-C (VEGF-C), VEGF-A, lymphatic vessel endothelial HA receptor-1 (LYVE-1) and CD34.Compared with the control group, the significantly increased expression of CD34 in mice of the EBSR group was observed, as well as expanded distribution. Also, a decrease in the early phase but a significant increase in the latter was seen in the expressions of VEGF-C, VEGF-A and LYVE-1.EBSR can up-regulate the expressions of VEGF-C, VEGF-A and LYVE-1 so as to promote liver angiogenesis of mice with partial hepatectomy." @default.
- W2414107035 created "2016-06-24" @default.
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- W2414107035 date "2015-04-01" @default.
- W2414107035 modified "2023-09-23" @default.
- W2414107035 title "[The extract of blackend swallowwort root up-regulates the expressions of angiogenesis related proteins and promotes liver angiogenesis of mice with partial hepatectomy]." @default.
- W2414107035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25854567" @default.
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