FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414153885> ?p ?o ?g. }

• W2414153885 endingPage "217" @default.
• W2414153885 startingPage "206" @default.
• W2414153885 abstract "Resveratrol may induce its neuroprotective effects by reducing oxidative damage and chronic inflammation apart from improving vascular function and activating longevity genes, it also has the ability to promote the activity of neurotrophic factors. Morphological changes in dendrites of the pyramidal neurons of the prefrontal cortex (PFC) and hippocampus have been reported in the brain of aging humans, or in humans with neurodegenerative diseases such as Alzheimer's disease. These changes are reflected particularly in the decrement of both the dendritic tree and spine density. Here we evaluated the effect of resveratrol on the dendrites of pyramidal neurons of the PFC (Layers 3 and 5), CA1- and CA3-dorsal hippocampus (DH) as well as CA1-ventral hippocampus, dentate gyrus (DG), and medium spiny neurons of the nucleus accumbens of aged rats. 18-month-old rats were administered resveratrol (20 mg/kg, orally) daily for 60 days. Dendritic morphology was studied by the Golgi-Cox stain procedure, followed by Sholl analysis on 20-month-old rats. In all resveratrol-treated rats, a significant increase in dendritic length and spine density in pyramidal neurons of the PFC, CA1, and CA3 of DH was observed. Interestingly, the enhancement in dendritic length was close to the soma in pyramidal neurons of the PFC, whereas in neurons of the DH and DG, the increase in dendritic length was further from the soma. Our results suggest that resveratrol induces modifications of dendritic morphology in the PFC, DH, and DG. These changes may explain the therapeutic effect of resveratrol in aging and in Alzheimer's disease." @default.
• W2414153885 created "2016-06-24" @default.
• W2414153885 creator A5012752153 @default.
• W2414153885 creator A5013687245 @default.
• W2414153885 creator A5030874100 @default.
• W2414153885 creator A5039635420 @default.
• W2414153885 creator A5069751789 @default.
• W2414153885 creator A5074566610 @default.
• W2414153885 creator A5080603956 @default.
• W2414153885 creator A5087951276 @default.
• W2414153885 date "2016-02-19" @default.
• W2414153885 modified "2023-10-12" @default.
• W2414153885 title "Chronic administration of resveratrol prevents morphological changes in prefrontal cortex and hippocampus of aged rats" @default.
• W2414153885 cites W1733395966 @default.
• W2414153885 cites W1777052256 @default.
• W2414153885 cites W1882365212 @default.
• W2414153885 cites W1899243102 @default.
• W2414153885 cites W1932137403 @default.
• W2414153885 cites W1964371958 @default.
• W2414153885 cites W1965997293 @default.
• W2414153885 cites W1966950577 @default.
• W2414153885 cites W1967638991 @default.
• W2414153885 cites W1971690948 @default.
• W2414153885 cites W1973311433 @default.
• W2414153885 cites W1976774123 @default.
• W2414153885 cites W1982441939 @default.
• W2414153885 cites W1993839684 @default.
• W2414153885 cites W1996583908 @default.
• W2414153885 cites W1999946931 @default.
• W2414153885 cites W2001195415 @default.
• W2414153885 cites W2009190178 @default.
• W2414153885 cites W2011522836 @default.
• W2414153885 cites W2015179821 @default.
• W2414153885 cites W2015270680 @default.
• W2414153885 cites W2015933608 @default.
• W2414153885 cites W2025018124 @default.
• W2414153885 cites W2027420199 @default.
• W2414153885 cites W2028200500 @default.
• W2414153885 cites W2028496416 @default.
• W2414153885 cites W2030382492 @default.
• W2414153885 cites W2038038139 @default.
• W2414153885 cites W2038440451 @default.
• W2414153885 cites W2040554582 @default.
• W2414153885 cites W2046678117 @default.
• W2414153885 cites W2051519554 @default.
• W2414153885 cites W2052556814 @default.
• W2414153885 cites W2053510668 @default.
• W2414153885 cites W2057178460 @default.
• W2414153885 cites W2058371877 @default.
• W2414153885 cites W2060929383 @default.
• W2414153885 cites W2064031606 @default.
• W2414153885 cites W2072480165 @default.
• W2414153885 cites W2074948025 @default.
• W2414153885 cites W2076962138 @default.
• W2414153885 cites W2084155803 @default.
• W2414153885 cites W2087680546 @default.
• W2414153885 cites W2093588085 @default.
• W2414153885 cites W2094759938 @default.
• W2414153885 cites W2097243895 @default.
• W2414153885 cites W2098655420 @default.
• W2414153885 cites W2100978260 @default.
• W2414153885 cites W2104999224 @default.
• W2414153885 cites W2107854911 @default.
• W2414153885 cites W2119657643 @default.
• W2414153885 cites W2120708979 @default.
• W2414153885 cites W2121869769 @default.
• W2414153885 cites W2125121177 @default.
• W2414153885 cites W2126619846 @default.
• W2414153885 cites W2133390798 @default.
• W2414153885 cites W2136747326 @default.
• W2414153885 cites W2138688273 @default.
• W2414153885 cites W2151089147 @default.
• W2414153885 cites W2154587590 @default.
• W2414153885 cites W2154927261 @default.
• W2414153885 cites W2161133182 @default.
• W2414153885 cites W2170591416 @default.
• W2414153885 cites W2341127480 @default.
• W2414153885 doi "https://doi.org/10.1002/syn.21888" @default.
• W2414153885 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26789275" @default.
• W2414153885 hasPublicationYear "2016" @default.
• W2414153885 type Work @default.
• W2414153885 sameAs 2414153885 @default.
• W2414153885 citedByCount "46" @default.
• W2414153885 countsByYear W24141538852016 @default.
• W2414153885 countsByYear W24141538852017 @default.
• W2414153885 countsByYear W24141538852018 @default.
• W2414153885 countsByYear W24141538852019 @default.
• W2414153885 countsByYear W24141538852020 @default.
• W2414153885 countsByYear W24141538852021 @default.
• W2414153885 countsByYear W24141538852022 @default.
• W2414153885 countsByYear W24141538852023 @default.
• W2414153885 crossrefType "journal-article" @default.
• W2414153885 hasAuthorship W2414153885A5012752153 @default.
• W2414153885 hasAuthorship W2414153885A5013687245 @default.
• W2414153885 hasAuthorship W2414153885A5030874100 @default.
• W2414153885 hasAuthorship W2414153885A5039635420 @default.
• W2414153885 hasAuthorship W2414153885A5069751789 @default.
• W2414153885 hasAuthorship W2414153885A5074566610 @default.

• next