Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414213862> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2414213862 endingPage "6" @default.
- W2414213862 startingPage "201" @default.
- W2414213862 abstract "House dust mites are a well known cause of asthma and other respiratory allergies. In order to improve the standardization of allergenic extracts for diagnosis and immunotherapy, it is important to determine the frequency and concentration of the components, both the major and the minor allergens during the growth period of the mite population. In a previous paper we demonstrated that the laboratory cultures of Dermatophagoides pteronyssinus and Dermatophogoides farinae exhibited three well differentiated growth phases: latency, exponential growth, and death of the culture. Biological standardization of extracts from the two mite species were carried out by skin prick tests in a group of 20 patients, using different concentrations of the extracts at the three growth phases. The patient sera were also studied by means of the RAST technique to determine the levels of specific IgE for each phase. The extracts produced from the exponential growth phase of the cultures revealed six times more relative allergenic activity in in vivo studies, and average RAST values were approximately three times higher than those extracts from latency and death phases. The reproducibility of the extract production method was assessed by comparing different batches obtained in similar conditions. The results showed batch-to-batch homogeneity allergenic activity. In conclusion, it was demonstrated that extracts obtained from cultures with the highest concentration of live mites (maximum growth phase) render the best diagnostic results in vivo and in vitro." @default.
- W2414213862 created "2016-06-24" @default.
- W2414213862 creator A5010684549 @default.
- W2414213862 creator A5010968169 @default.
- W2414213862 creator A5050887248 @default.
- W2414213862 creator A5051723693 @default.
- W2414213862 creator A5054917224 @default.
- W2414213862 creator A5061145818 @default.
- W2414213862 creator A5070413074 @default.
- W2414213862 date "1998-10-20" @default.
- W2414213862 modified "2023-09-23" @default.
- W2414213862 title "Influence of mite growth culture phases on the biological standardization of allergenic extracts." @default.
- W2414213862 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9777533" @default.
- W2414213862 hasPublicationYear "1998" @default.
- W2414213862 type Work @default.
- W2414213862 sameAs 2414213862 @default.
- W2414213862 citedByCount "8" @default.
- W2414213862 countsByYear W24142138622012 @default.
- W2414213862 countsByYear W24142138622015 @default.
- W2414213862 crossrefType "journal-article" @default.
- W2414213862 hasAuthorship W2414213862A5010684549 @default.
- W2414213862 hasAuthorship W2414213862A5010968169 @default.
- W2414213862 hasAuthorship W2414213862A5050887248 @default.
- W2414213862 hasAuthorship W2414213862A5051723693 @default.
- W2414213862 hasAuthorship W2414213862A5054917224 @default.
- W2414213862 hasAuthorship W2414213862A5061145818 @default.
- W2414213862 hasAuthorship W2414213862A5070413074 @default.
- W2414213862 hasConcept C150903083 @default.
- W2414213862 hasConcept C203014093 @default.
- W2414213862 hasConcept C207001950 @default.
- W2414213862 hasConcept C207480886 @default.
- W2414213862 hasConcept C2779711295 @default.
- W2414213862 hasConcept C2780510475 @default.
- W2414213862 hasConcept C2908647359 @default.
- W2414213862 hasConcept C31903555 @default.
- W2414213862 hasConcept C59822182 @default.
- W2414213862 hasConcept C71924100 @default.
- W2414213862 hasConcept C86803240 @default.
- W2414213862 hasConcept C99454951 @default.
- W2414213862 hasConceptScore W2414213862C150903083 @default.
- W2414213862 hasConceptScore W2414213862C203014093 @default.
- W2414213862 hasConceptScore W2414213862C207001950 @default.
- W2414213862 hasConceptScore W2414213862C207480886 @default.
- W2414213862 hasConceptScore W2414213862C2779711295 @default.
- W2414213862 hasConceptScore W2414213862C2780510475 @default.
- W2414213862 hasConceptScore W2414213862C2908647359 @default.
- W2414213862 hasConceptScore W2414213862C31903555 @default.
- W2414213862 hasConceptScore W2414213862C59822182 @default.
- W2414213862 hasConceptScore W2414213862C71924100 @default.
- W2414213862 hasConceptScore W2414213862C86803240 @default.
- W2414213862 hasConceptScore W2414213862C99454951 @default.
- W2414213862 hasIssue "4" @default.
- W2414213862 hasLocation W24142138621 @default.
- W2414213862 hasOpenAccess W2414213862 @default.
- W2414213862 hasPrimaryLocation W24142138621 @default.
- W2414213862 hasRelatedWork W184119238 @default.
- W2414213862 hasRelatedWork W1959051376 @default.
- W2414213862 hasRelatedWork W2005843091 @default.
- W2414213862 hasRelatedWork W2037019085 @default.
- W2414213862 hasRelatedWork W2065426285 @default.
- W2414213862 hasRelatedWork W2093685379 @default.
- W2414213862 hasRelatedWork W2117139404 @default.
- W2414213862 hasRelatedWork W2152722283 @default.
- W2414213862 hasRelatedWork W2397721745 @default.
- W2414213862 hasRelatedWork W4254700692 @default.
- W2414213862 hasVolume "8" @default.
- W2414213862 isParatext "false" @default.
- W2414213862 isRetracted "false" @default.
- W2414213862 magId "2414213862" @default.
- W2414213862 workType "article" @default.