Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414339322> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2414339322 endingPage "72" @default.
- W2414339322 startingPage "962" @default.
- W2414339322 abstract "We have investigated the in vivo biosynthesis of the minor hemoglobin components in the rhesus monkey. The elution profile of rhesus hemolysate on BioRex 70 cation exchange resin was analogous to that of human hemolysate. The rhesus Hb Alc peak was identified with the TBA test, which revealed a carbohydrate content identical to that of human Hb A1c. A rhesus monkey was injected with autologous 55Fe-bound transferrin, and the specific activity of each of the minor and major components was followed for over 70 days. As previously shown in man, rhesus Hb alc accumulated specific activity almost linearly over the erythrocyte life-span, indicative of slow and continuous conversion of Hb A0 to Hb Alc. This study revealed two new findings. (1) The specific activity of rhesus Hb Alb was always significantly less than that of Hb Alc. This result suggested that HB Alb is made by further posttranslational modification of Hb Alc. (2) The first portion of rhesus Hb A0 to be eluted on BioRex 70 contained a significant amount of carbohydrate and lower initial specific radioactivity than did the latter portion. This unexpected heterogeneity in the major hemoglobin component reflects slow, nonenzymatic glycosylation at sites other than at the N-terminus of the beta-chain." @default.
- W2414339322 created "2016-06-24" @default.
- W2414339322 creator A5018554668 @default.
- W2414339322 creator A5023208717 @default.
- W2414339322 creator A5030124621 @default.
- W2414339322 creator A5052103601 @default.
- W2414339322 creator A5062071449 @default.
- W2414339322 creator A5074516755 @default.
- W2414339322 date "1979-06-01" @default.
- W2414339322 modified "2023-09-23" @default.
- W2414339322 title "Biosynthesis of glycosylated hemoglobins in the monkey." @default.
- W2414339322 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/108346" @default.
- W2414339322 hasPublicationYear "1979" @default.
- W2414339322 type Work @default.
- W2414339322 sameAs 2414339322 @default.
- W2414339322 citedByCount "3" @default.
- W2414339322 crossrefType "journal-article" @default.
- W2414339322 hasAuthorship W2414339322A5018554668 @default.
- W2414339322 hasAuthorship W2414339322A5023208717 @default.
- W2414339322 hasAuthorship W2414339322A5030124621 @default.
- W2414339322 hasAuthorship W2414339322A5052103601 @default.
- W2414339322 hasAuthorship W2414339322A5062071449 @default.
- W2414339322 hasAuthorship W2414339322A5074516755 @default.
- W2414339322 hasConcept C153911025 @default.
- W2414339322 hasConcept C181199279 @default.
- W2414339322 hasConcept C185592680 @default.
- W2414339322 hasConcept C202751555 @default.
- W2414339322 hasConcept C207001950 @default.
- W2414339322 hasConcept C2777313579 @default.
- W2414339322 hasConcept C2778917026 @default.
- W2414339322 hasConcept C2778977261 @default.
- W2414339322 hasConcept C54355233 @default.
- W2414339322 hasConcept C553450214 @default.
- W2414339322 hasConcept C55493867 @default.
- W2414339322 hasConcept C86803240 @default.
- W2414339322 hasConceptScore W2414339322C153911025 @default.
- W2414339322 hasConceptScore W2414339322C181199279 @default.
- W2414339322 hasConceptScore W2414339322C185592680 @default.
- W2414339322 hasConceptScore W2414339322C202751555 @default.
- W2414339322 hasConceptScore W2414339322C207001950 @default.
- W2414339322 hasConceptScore W2414339322C2777313579 @default.
- W2414339322 hasConceptScore W2414339322C2778917026 @default.
- W2414339322 hasConceptScore W2414339322C2778977261 @default.
- W2414339322 hasConceptScore W2414339322C54355233 @default.
- W2414339322 hasConceptScore W2414339322C553450214 @default.
- W2414339322 hasConceptScore W2414339322C55493867 @default.
- W2414339322 hasConceptScore W2414339322C86803240 @default.
- W2414339322 hasIssue "6" @default.
- W2414339322 hasLocation W24143393221 @default.
- W2414339322 hasOpenAccess W2414339322 @default.
- W2414339322 hasPrimaryLocation W24143393221 @default.
- W2414339322 hasRelatedWork W1978239175 @default.
- W2414339322 hasRelatedWork W1978895765 @default.
- W2414339322 hasRelatedWork W2004562246 @default.
- W2414339322 hasRelatedWork W2157954516 @default.
- W2414339322 hasRelatedWork W2366713136 @default.
- W2414339322 hasRelatedWork W2397237675 @default.
- W2414339322 hasRelatedWork W2400498648 @default.
- W2414339322 hasRelatedWork W2733724482 @default.
- W2414339322 hasRelatedWork W4246750412 @default.
- W2414339322 hasRelatedWork W752283992 @default.
- W2414339322 hasVolume "93" @default.
- W2414339322 isParatext "false" @default.
- W2414339322 isRetracted "false" @default.
- W2414339322 magId "2414339322" @default.
- W2414339322 workType "article" @default.