FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414399053> ?p ?o ?g. }

• W2414399053 endingPage "448" @default.
• W2414399053 startingPage "442" @default.
• W2414399053 abstract "ABSTRACT Objective: Functional in vitro studies are fundamental to understand the role of microRNAs, small non coding RNA molecules that function as post-transcriptional regulators, in cancer. The objective of this study was to determine the applicability of head and neck squamous cell carcinoma cell lines and human oral keratinocytes as models for functional studies on microRNAs previously identified as deregulated in head and neck squamous cell carcinomas. Methods: The expression level of four microRNAs was assessed in cell lines and in primary cultures of oral keratinocytes using specific real-time polymerase chain reactions. The identity of oral squamous cell carcinoma cell lines was confirmed by means of STR (short tandem repeats) profiling. The possible impact of feeder-layer gene expression in global microRNA expression results from keratinocyte primary culture was also evaluated. Results: Significant differences in microRNA gene expression were observed among squamous cell carcinoma cell lines, particularly among cells lines from distinct subsites, as well as between primary culture of human keratinocytes and immortalized keratinocyte cell lines. Conclusions: Primary cultures of human keratinocytes and diverse tumor cell lines are relatively easy to obtain. However, each cell model possesses a characteristic phenotype; whereas one may be useful for a specific study, it may be inappropriate for another. Therefore, it is imperative that suitable cell lines are cautiously selected for functional studies in cancer." @default.
• W2414399053 created "2016-06-24" @default.
• W2414399053 creator A5012537611 @default.
• W2414399053 creator A5017571232 @default.
• W2414399053 creator A5022386316 @default.
• W2414399053 creator A5027816036 @default.
• W2414399053 creator A5049508116 @default.
• W2414399053 creator A5058962034 @default.
• W2414399053 creator A5059504867 @default.
• W2414399053 creator A5075103961 @default.
• W2414399053 date "2011-12-01" @default.
• W2414399053 modified "2023-09-26" @default.
• W2414399053 title "Evaluation of microRNA expression in head and neck squamous cell carcinoma cell lines and in primary culture of oral keratinocytes" @default.
• W2414399053 cites W1989039826 @default.
• W2414399053 cites W1990521145 @default.
• W2414399053 cites W1997508254 @default.
• W2414399053 cites W2009183417 @default.
• W2414399053 cites W2015858554 @default.
• W2414399053 cites W2022030509 @default.
• W2414399053 cites W2027855079 @default.
• W2414399053 cites W2041731495 @default.
• W2414399053 cites W2061379163 @default.
• W2414399053 cites W2068703601 @default.
• W2414399053 cites W2074259284 @default.
• W2414399053 cites W2085082345 @default.
• W2414399053 cites W2089858439 @default.
• W2414399053 cites W2108332050 @default.
• W2414399053 cites W2112845420 @default.
• W2414399053 cites W2113725788 @default.
• W2414399053 cites W2151922790 @default.
• W2414399053 cites W2152261156 @default.
• W2414399053 cites W2158734599 @default.
• W2414399053 cites W2160033023 @default.
• W2414399053 cites W2163199119 @default.
• W2414399053 cites W2165460739 @default.
• W2414399053 cites W4301147396 @default.
• W2414399053 cites W4361804794 @default.
• W2414399053 cites W3149786887 @default.
• W2414399053 doi "https://doi.org/10.1590/s1679-45082011ao2149" @default.
• W2414399053 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26761243" @default.
• W2414399053 hasPublicationYear "2011" @default.
• W2414399053 type Work @default.
• W2414399053 sameAs 2414399053 @default.
• W2414399053 citedByCount "1" @default.
• W2414399053 countsByYear W24143990532016 @default.
• W2414399053 crossrefType "journal-article" @default.
• W2414399053 hasAuthorship W2414399053A5012537611 @default.
• W2414399053 hasAuthorship W2414399053A5017571232 @default.
• W2414399053 hasAuthorship W2414399053A5022386316 @default.
• W2414399053 hasAuthorship W2414399053A5027816036 @default.
• W2414399053 hasAuthorship W2414399053A5049508116 @default.
• W2414399053 hasAuthorship W2414399053A5058962034 @default.
• W2414399053 hasAuthorship W2414399053A5059504867 @default.
• W2414399053 hasAuthorship W2414399053A5075103961 @default.
• W2414399053 hasBestOaLocation W24143990531 @default.
• W2414399053 hasConcept C104317684 @default.
• W2414399053 hasConcept C121608353 @default.
• W2414399053 hasConcept C145059251 @default.
• W2414399053 hasConcept C1491633281 @default.
• W2414399053 hasConcept C150194340 @default.
• W2414399053 hasConcept C18431079 @default.
• W2414399053 hasConcept C2776530083 @default.
• W2414399053 hasConcept C2776833033 @default.
• W2414399053 hasConcept C2777074287 @default.
• W2414399053 hasConcept C2994460389 @default.
• W2414399053 hasConcept C502942594 @default.
• W2414399053 hasConcept C54355233 @default.
• W2414399053 hasConcept C6045943 @default.
• W2414399053 hasConcept C81885089 @default.
• W2414399053 hasConcept C86803240 @default.
• W2414399053 hasConceptScore W2414399053C104317684 @default.
• W2414399053 hasConceptScore W2414399053C121608353 @default.
• W2414399053 hasConceptScore W2414399053C145059251 @default.
• W2414399053 hasConceptScore W2414399053C1491633281 @default.
• W2414399053 hasConceptScore W2414399053C150194340 @default.
• W2414399053 hasConceptScore W2414399053C18431079 @default.
• W2414399053 hasConceptScore W2414399053C2776530083 @default.
• W2414399053 hasConceptScore W2414399053C2776833033 @default.
• W2414399053 hasConceptScore W2414399053C2777074287 @default.
• W2414399053 hasConceptScore W2414399053C2994460389 @default.
• W2414399053 hasConceptScore W2414399053C502942594 @default.
• W2414399053 hasConceptScore W2414399053C54355233 @default.
• W2414399053 hasConceptScore W2414399053C6045943 @default.
• W2414399053 hasConceptScore W2414399053C81885089 @default.
• W2414399053 hasConceptScore W2414399053C86803240 @default.
• W2414399053 hasIssue "4" @default.
• W2414399053 hasLocation W24143990531 @default.
• W2414399053 hasLocation W24143990532 @default.
• W2414399053 hasLocation W24143990533 @default.
• W2414399053 hasLocation W24143990534 @default.
• W2414399053 hasOpenAccess W2414399053 @default.
• W2414399053 hasPrimaryLocation W24143990531 @default.
• W2414399053 hasRelatedWork W166274801 @default.
• W2414399053 hasRelatedWork W1988455047 @default.
• W2414399053 hasRelatedWork W2015581780 @default.
• W2414399053 hasRelatedWork W2061035876 @default.
• W2414399053 hasRelatedWork W2066815315 @default.
• W2414399053 hasRelatedWork W2068335451 @default.

• next