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- W2414401850 abstract "To review the pathophysiology, co-morbidities, and therapeutic options for psoriasis, psoriatic arthritis and rheumatoid arthritis in order to further understand the similarities and differences in treatment paradigms in the management of each disease. New targets for individualized therapeutic decisions are also identified with the aim of improving therapeutic outcome and reducing toxicity.Using the PubMed database, we searched literature published from 2000 to 2015 using combinations of the key words psoriasis, psoriatic arthritis, rheumatoid arthritis, pathogenesis, immunomodulation, and treatment.This was a non-systematic review and there were no formal inclusion and exclusion criteria.Abstracts identified in the search were screened for relevance and articles considered appropriate evaluated further. References within these selected articles were also screened. Information was extracted from 198 articles for inclusion in this report.There was no formal data synthesis. Articles were reviewed and summarized according to disease area (psoriasis, psoriatic arthritis, and rheumatoid arthritis).The pathophysiology of psoriasis, psoriatic arthritis, and rheumatoid arthritis involves chronic inflammation mediated by pro-inflammatory cytokines. Dysfunction in integrated signaling pathways affecting different constituents of the immune system result in varying clinical features in the three diseases. Co-morbidities, including cardiovascular disease, malignancies, and non-alcoholic fatty liver disease are increased. Increased understanding of the immunopathogenesis allowed development of targeted treatments; however, despite a variety of potentially predictive genetic, protein and cellular biomarkers, there is still significant unmet need in these three inflammatory disorders." @default.
- W2414401850 created "2016-06-24" @default.
- W2414401850 creator A5020129995 @default.
- W2414401850 creator A5051239558 @default.
- W2414401850 creator A5077643606 @default.
- W2414401850 creator A5085522760 @default.
- W2414401850 date "2016-12-01" @default.
- W2414401850 modified "2023-10-10" @default.
- W2414401850 title "Psoriasis, psoriatic arthritis, and rheumatoid arthritis: Is all inflammation the same?" @default.
- W2414401850 cites W1515219927 @default.
- W2414401850 cites W1528172769 @default.
- W2414401850 cites W1533030532 @default.
- W2414401850 cites W1541596409 @default.
- W2414401850 cites W1548769791 @default.
- W2414401850 cites W1564680778 @default.
- W2414401850 cites W1565944332 @default.
- W2414401850 cites W1591809044 @default.
- W2414401850 cites W1599017652 @default.
- W2414401850 cites W1616565396 @default.
- W2414401850 cites W1720332280 @default.
- W2414401850 cites W1761300068 @default.
- W2414401850 cites W1792727815 @default.
- W2414401850 cites W1834455687 @default.
- W2414401850 cites W1859531625 @default.
- W2414401850 cites W1915760257 @default.
- W2414401850 cites W1926302666 @default.
- W2414401850 cites W1963627597 @default.
- W2414401850 cites W1965007203 @default.
- W2414401850 cites W1965656481 @default.
- W2414401850 cites W1968321227 @default.
- W2414401850 cites W1969186806 @default.
- W2414401850 cites W1972491378 @default.
- W2414401850 cites W1973354423 @default.
- W2414401850 cites W1975091847 @default.
- W2414401850 cites W1977445011 @default.
- W2414401850 cites W1980827798 @default.
- W2414401850 cites W1982292637 @default.
- W2414401850 cites W1982351641 @default.
- W2414401850 cites W1982549552 @default.
- W2414401850 cites W1983619409 @default.
- W2414401850 cites W1987784314 @default.
- W2414401850 cites W1988318286 @default.
- W2414401850 cites W1992872974 @default.
- W2414401850 cites W1996677952 @default.
- W2414401850 cites W1997273242 @default.
- W2414401850 cites W1997282832 @default.
- W2414401850 cites W1997817841 @default.
- W2414401850 cites W1997925342 @default.
- W2414401850 cites W2000061875 @default.
- W2414401850 cites W2000851235 @default.
- W2414401850 cites W2002459476 @default.
- W2414401850 cites W2008710073 @default.
- W2414401850 cites W2008727668 @default.
- W2414401850 cites W2010277266 @default.
- W2414401850 cites W2011224074 @default.
- W2414401850 cites W2013886298 @default.
- W2414401850 cites W2016834798 @default.
- W2414401850 cites W2016954098 @default.
- W2414401850 cites W2017008393 @default.
- W2414401850 cites W2017602032 @default.
- W2414401850 cites W2019217317 @default.
- W2414401850 cites W2019383068 @default.
- W2414401850 cites W2020233428 @default.
- W2414401850 cites W2021018799 @default.
- W2414401850 cites W2021710624 @default.
- W2414401850 cites W2022219453 @default.
- W2414401850 cites W2022258009 @default.
- W2414401850 cites W2022665587 @default.
- W2414401850 cites W2024272597 @default.
- W2414401850 cites W2026757352 @default.
- W2414401850 cites W2028621745 @default.
- W2414401850 cites W2031064470 @default.
- W2414401850 cites W2033342396 @default.
- W2414401850 cites W2035320881 @default.
- W2414401850 cites W2035973303 @default.
- W2414401850 cites W2037882607 @default.
- W2414401850 cites W2040109162 @default.
- W2414401850 cites W2040733258 @default.
- W2414401850 cites W2041802424 @default.
- W2414401850 cites W2043390209 @default.
- W2414401850 cites W2043490207 @default.
- W2414401850 cites W2044570122 @default.
- W2414401850 cites W2045113343 @default.
- W2414401850 cites W2052364506 @default.
- W2414401850 cites W2054678820 @default.
- W2414401850 cites W2055552847 @default.
- W2414401850 cites W2056510298 @default.
- W2414401850 cites W2056525982 @default.
- W2414401850 cites W2056558169 @default.
- W2414401850 cites W2061869766 @default.
- W2414401850 cites W2064711537 @default.
- W2414401850 cites W2065751595 @default.
- W2414401850 cites W2066418530 @default.
- W2414401850 cites W2069302785 @default.
- W2414401850 cites W2069346187 @default.
- W2414401850 cites W2074205207 @default.
- W2414401850 cites W2074679120 @default.
- W2414401850 cites W2075689919 @default.