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- W2414426331 abstract "Objective To compare the applicability of the three diagnostic criteria for metabolic syndrome (MS) proposed by the International Diabetes Federation(IDF) in 2005 ,Adult Treatment Panel Ⅲ of National Cholesterol Education Program(NCEP-ATP Ⅲ) in 2005 and Chinese Diabetes Socie(CDS) in 2004. Methods Based on the findings of cohort study of multiple metabolic disorders and metabolic syndrome (1971 cases) in Jiangsu province, MS was diagnosed according to these three definitions respectively,and by calculating the sensitivity, specificity, and ROC curve distance, those with lower false positive and false negative rates were identified as to detecting cardio vascular diseases(CVD) and type 2 diabetes mellitus(T2DM). While, through Cox regression analysis, to compare their relative risk (RR) and 95% confidential interval (CI)was wade. Results Among three diagnostic criteria,the specificity by CDS of MS was higher than the other criteria (83.52%, 76. 36%, 89. 57% ; 85.02%, 78. 67%, 92. 28%), however the sensitivity of CDS of MS was low (40. 82% , 29.47%). When using CDS, over 50 percent of diagnosis might be missed. ATP Ⅲ definition corresponded to the shortest distance in ROC curve,namely,at the diagnostic criteria, the rates of false positive and false negative for identifying clustering of CVD and T2DM were minimum(0. 4369; 0. 5777). The incidence of CVD [5.59 (2. 62 - 11.92) vs 2.90 (1.41 -5.93)],T2DM [3.36(1.92 -5.79) vs 1.97 (1.16 -3.34)] was significantly higher in cases of ATPⅢ +/IDF- than ATP Ⅲ +/IDF +, as compared with ATP Ⅲ -/IDF -. Conclusion Among three diagnostic criteria,the ATP Ⅲ definition of the MS should be the most applicable diagnostic criteria for MS in Jiangsu population.Key words: Metabolic syndrome; Diagnostic criteria; Applicability" @default.
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- W2414426331 date "2009-02-01" @default.
- W2414426331 modified "2023-09-22" @default.
- W2414426331 title "A comparison of applicability in three diagnostic criteria of metabolic syndrome in Jiangsu population" @default.
- W2414426331 doi "https://doi.org/10.3760/cma.j.issn.0253-9624.2009.02.007" @default.
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