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- W2414461573 abstract "pT4 is a group of miscellaneous tumors: our goal was to revisit their surgical reality.The different characteristics and prognostic factors of lung pT4 (n=403) were analysed according to three subgroups: G1 - by direct extension; G2 - by nodule in other ipsilateral lobe; G3 - because of both.There were 332 males and 71 females mean aged 61.5 years. Surgery [exploratory: 89 (22.1 %), lobectomy: 149 (37 %), pneumonectomy: 169 (41.9 %)] was followed by 26 postoperative deaths (6.5 %), 82 complications (20.3 %) and concerned few pN0 (47.6 %). G1 (n=196) and G3 (n=53) were not different. By comparison with them, G2 (n=53) were mainly females (2413 %), with less explorative thoracotomy (2.634 %), more complete R0 resections (7729 %), less pneumonectomy (3147 %), more small sized tumors (mean: 3757 mm), more adenocarcinoma (6732 %), more N0 tumors (4831.7 %) and stages IIIA disease (46.756 %). G2 5-year survival rates were higher (G2: 22 %; G1: 13 %; G3: 15 %); G1 rates depended of the invaded structure (20.9 % for the vertebra down to 0 % for the esophagus and carina). pN2 rates were not very high but not different between groups (G1: 13.6 %; G2: 15.6 %; G3: 14.3 %; P=0.52). Multivariate analysis demonstrated completeness and type of resection, stage and age as independent factors of prognosis.Surgery for pT4 is justified provided rigorous selection of extension forms. However, assimilating extension and ipsilateral lobe nodule in a same group does not obey to surgical reality." @default.
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- W2414461573 date "2014-08-01" @default.
- W2414461573 modified "2023-10-18" @default.
- W2414461573 title "Cancers du poumon non à petites cellules pT4 : aspects chirurgicaux en pratique courante" @default.
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- W2414461573 doi "https://doi.org/10.1016/j.pneumo.2014.02.004" @default.
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