Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414465758> ?p ?o ?g. }
Showing items 1 to 54 of
54
with 100 items per page.
- W2414465758 endingPage "8" @default.
- W2414465758 startingPage "S155" @default.
- W2414465758 abstract "A controlled study was conducted in hypertensive patients to investigate whether captopril can be substituted for the various other antihypertensive drugs (not including diuretics) to reduce side effects and improve the quality of life. Captopril in a twice daily dose of 25-50 mg, was substituted and titrated in 54 patients. Fifty-two patients, matched by age and sex, comprised the control group, and were treated with a variety of agents. During a follow-up of 9 months, 44 of the patients receiving captopril (81%) achieved the goal of supine blood pressure less than 90 mmHg. Captopril was discontinued in two patients due to side effects. Mild proteinuria was observed in two patients. A significant reduction in scores or rates of side effects (numbness, blurred vision, insomnia, vivid dreams, cold extremities, sleepiness, sexual dysfunction and fatigue) and improvement in quality of life (general feeling, mood and concentration) was observed in the study group compared with the control group. Captopril alone in a twice daily dose of 25-50 mg, or in co-treatment with thiazide, provided sustained blood pressure control with minimal side effects and improvement in quality of life compared with the treatment of hypertension with beta-blockers, vasodilators or methyldopa." @default.
- W2414465758 created "2016-06-24" @default.
- W2414465758 creator A5000778736 @default.
- W2414465758 creator A5048655697 @default.
- W2414465758 creator A5075043007 @default.
- W2414465758 date "1985-11-01" @default.
- W2414465758 modified "2023-09-27" @default.
- W2414465758 title "Captopril as a replacement for multiple therapy in hypertension: a controlled study." @default.
- W2414465758 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3910775" @default.
- W2414465758 hasPublicationYear "1985" @default.
- W2414465758 type Work @default.
- W2414465758 sameAs 2414465758 @default.
- W2414465758 citedByCount "2" @default.
- W2414465758 crossrefType "journal-article" @default.
- W2414465758 hasAuthorship W2414465758A5000778736 @default.
- W2414465758 hasAuthorship W2414465758A5048655697 @default.
- W2414465758 hasAuthorship W2414465758A5075043007 @default.
- W2414465758 hasConcept C125567185 @default.
- W2414465758 hasConcept C126322002 @default.
- W2414465758 hasConcept C159110408 @default.
- W2414465758 hasConcept C2779479957 @default.
- W2414465758 hasConcept C2779951463 @default.
- W2414465758 hasConcept C42219234 @default.
- W2414465758 hasConcept C71924100 @default.
- W2414465758 hasConcept C84393581 @default.
- W2414465758 hasConceptScore W2414465758C125567185 @default.
- W2414465758 hasConceptScore W2414465758C126322002 @default.
- W2414465758 hasConceptScore W2414465758C159110408 @default.
- W2414465758 hasConceptScore W2414465758C2779479957 @default.
- W2414465758 hasConceptScore W2414465758C2779951463 @default.
- W2414465758 hasConceptScore W2414465758C42219234 @default.
- W2414465758 hasConceptScore W2414465758C71924100 @default.
- W2414465758 hasConceptScore W2414465758C84393581 @default.
- W2414465758 hasIssue "2" @default.
- W2414465758 hasLocation W24144657581 @default.
- W2414465758 hasOpenAccess W2414465758 @default.
- W2414465758 hasPrimaryLocation W24144657581 @default.
- W2414465758 hasRelatedWork W105106622 @default.
- W2414465758 hasRelatedWork W1971805416 @default.
- W2414465758 hasRelatedWork W1976346162 @default.
- W2414465758 hasRelatedWork W2009369612 @default.
- W2414465758 hasRelatedWork W2062596130 @default.
- W2414465758 hasRelatedWork W2071554631 @default.
- W2414465758 hasRelatedWork W2084992408 @default.
- W2414465758 hasRelatedWork W2086063024 @default.
- W2414465758 hasRelatedWork W2097742979 @default.
- W2414465758 hasRelatedWork W2417165001 @default.
- W2414465758 hasVolume "3" @default.
- W2414465758 isParatext "false" @default.
- W2414465758 isRetracted "false" @default.
- W2414465758 magId "2414465758" @default.
- W2414465758 workType "article" @default.