FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414522> ?p ?o ?g. }

• W2414522 endingPage "286" @default.
• W2414522 startingPage "273" @default.
• W2414522 abstract "Acute Q fever is commonly resolved without an antibiotic regimen, but a primary infection may develop into a chronic infection in a minority of cases. Coxiella burnetii, the causative agent of Q fever, is known to infect macrophages both in vitro and in vivo. It has been observed that the intracellular survival of C. burnetii requires the subversion of the microbicidal properties of macrophages. Adaptive immunity is also essential to cure C. burnetii infection, as demonstrated by clinical studies and animal models. Indeed, the control of infection in patients with primary Q fever involves a systemic cell-mediated immune response and granuloma formation with an essential role for interferon-γ in the protection against C. burnetii. In contrast, chronic Q fever is characterized by defective cell-mediated immunity with the defective formation of granulomas and over-production of interleukin-10, an immunoregulatory cytokine. Finally, epidemiological data demonstrate that age and gender are risk factors for Q fever. The analysis of gene expression programs in mice reveals the importance of sex-related genes in C. burnetii infection because only 14% of the modulated genes are sex-independent, while the remaining 86% are differentially expressed in males and females. These results open a new field to understand how host metabolism controls C. burnetii infection in humans." @default.
• W2414522 created "2016-06-24" @default.
• W2414522 creator A5035168503 @default.
• W2414522 creator A5059466600 @default.
• W2414522 date "2012-01-01" @default.
• W2414522 modified "2023-09-23" @default.
• W2414522 title "Role of Innate and Adaptive Immunity in the Control of Q Fever" @default.
• W2414522 cites W1598858589 @default.
• W2414522 cites W1821540296 @default.
• W2414522 cites W1883203342 @default.
• W2414522 cites W1904569031 @default.
• W2414522 cites W1915485552 @default.
• W2414522 cites W1931043691 @default.
• W2414522 cites W1934913571 @default.
• W2414522 cites W1963886255 @default.
• W2414522 cites W1965936817 @default.
• W2414522 cites W1980670955 @default.
• W2414522 cites W1981174792 @default.
• W2414522 cites W1984543511 @default.
• W2414522 cites W1987490732 @default.
• W2414522 cites W1990267308 @default.
• W2414522 cites W1993070584 @default.
• W2414522 cites W1996052697 @default.
• W2414522 cites W1997657977 @default.
• W2414522 cites W1998465006 @default.
• W2414522 cites W2002705506 @default.
• W2414522 cites W2004101198 @default.
• W2414522 cites W2007712574 @default.
• W2414522 cites W2037610354 @default.
• W2414522 cites W2041570680 @default.
• W2414522 cites W2044884968 @default.
• W2414522 cites W2047997726 @default.
• W2414522 cites W2048291670 @default.
• W2414522 cites W2054988689 @default.
• W2414522 cites W2067776060 @default.
• W2414522 cites W2076796449 @default.
• W2414522 cites W2093225609 @default.
• W2414522 cites W2095736829 @default.
• W2414522 cites W2097561709 @default.
• W2414522 cites W2099874610 @default.
• W2414522 cites W2103256564 @default.
• W2414522 cites W2103451304 @default.
• W2414522 cites W2118514507 @default.
• W2414522 cites W2121948788 @default.
• W2414522 cites W2123063744 @default.
• W2414522 cites W2127857908 @default.
• W2414522 cites W2130007846 @default.
• W2414522 cites W2130477547 @default.
• W2414522 cites W2130787440 @default.
• W2414522 cites W2131634519 @default.
• W2414522 cites W2134665721 @default.
• W2414522 cites W2134715322 @default.
• W2414522 cites W2134903749 @default.
• W2414522 cites W2140625118 @default.
• W2414522 cites W2152604438 @default.
• W2414522 cites W2154321924 @default.
• W2414522 cites W2154367684 @default.
• W2414522 cites W2154934888 @default.
• W2414522 cites W2158739281 @default.
• W2414522 cites W2159075440 @default.
• W2414522 cites W2169336589 @default.
• W2414522 cites W2171195635 @default.
• W2414522 cites W2171772350 @default.
• W2414522 cites W2172266327 @default.
• W2414522 cites W3022450908 @default.
• W2414522 cites W4211219679 @default.
• W2414522 cites W4242041143 @default.
• W2414522 cites W4299719535 @default.
• W2414522 cites W4313341536 @default.
• W2414522 doi "https://doi.org/10.1007/978-94-007-4315-1_14" @default.
• W2414522 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22711637" @default.
• W2414522 hasPublicationYear "2012" @default.
• W2414522 type Work @default.
• W2414522 sameAs 2414522 @default.
• W2414522 citedByCount "19" @default.
• W2414522 countsByYear W24145222013 @default.
• W2414522 countsByYear W24145222014 @default.
• W2414522 countsByYear W24145222015 @default.
• W2414522 countsByYear W24145222016 @default.
• W2414522 countsByYear W24145222017 @default.
• W2414522 countsByYear W24145222018 @default.
• W2414522 countsByYear W24145222019 @default.
• W2414522 countsByYear W24145222020 @default.
• W2414522 countsByYear W24145222021 @default.
• W2414522 countsByYear W24145222022 @default.
• W2414522 crossrefType "book-chapter" @default.
• W2414522 hasAuthorship W2414522A5035168503 @default.
• W2414522 hasAuthorship W2414522A5059466600 @default.
• W2414522 hasConcept C136449434 @default.
• W2414522 hasConcept C159047783 @default.
• W2414522 hasConcept C193419808 @default.
• W2414522 hasConcept C203014093 @default.
• W2414522 hasConcept C2522874641 @default.
• W2414522 hasConcept C2776607032 @default.
• W2414522 hasConcept C2779341262 @default.
• W2414522 hasConcept C2780414542 @default.
• W2414522 hasConcept C2780731870 @default.
• W2414522 hasConcept C86803240 @default.

• next