Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414543630> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2414543630 endingPage "67" @default.
- W2414543630 startingPage "459" @default.
- W2414543630 abstract "Ulcerative colitis is a chronic inflammatory condition of the large intestine whose etiology remains largely unknown. Its pathogenesis involves the breakdown of intestinal mucosal homeostasis due to a genetically determined miscommunication between commensal flora and the gut associated immune system. Cytokines are central components of the inflammatory pathways that take place during the active and chronic phases of ulcerative colitis. Recent research has identified several novel cytokine systems that are upregulated at the mucosa of patients with ulcerative colitis and started to unveil their functional importance for disease pathogenesis. The significance of interleukin-13 (IL-13), TNF-like cytokine 1A (TL1A), IL-33, and their receptors in ulcerative colitis is strongly supported by converging expression and functional data. These molecular systems may define subgroups of patients with uniform immunological profiles. Within these subpopulations such novel cytokine systems may serve as markers of biological activity of the disease. More importantly, they may offer unique therapeutic opportunities through the development of drugs that specifically target and neutralize well-defined inflammatory pathways." @default.
- W2414543630 created "2016-06-24" @default.
- W2414543630 creator A5017092378 @default.
- W2414543630 creator A5018987384 @default.
- W2414543630 creator A5091219809 @default.
- W2414543630 date "2011-05-01" @default.
- W2414543630 modified "2023-10-03" @default.
- W2414543630 title "Cytokines in the pathogenesis of ulcerative colitis." @default.
- W2414543630 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21616044" @default.
- W2414543630 hasPublicationYear "2011" @default.
- W2414543630 type Work @default.
- W2414543630 sameAs 2414543630 @default.
- W2414543630 citedByCount "18" @default.
- W2414543630 countsByYear W24145436302012 @default.
- W2414543630 countsByYear W24145436302013 @default.
- W2414543630 countsByYear W24145436302014 @default.
- W2414543630 countsByYear W24145436302016 @default.
- W2414543630 countsByYear W24145436302018 @default.
- W2414543630 countsByYear W24145436302019 @default.
- W2414543630 countsByYear W24145436302020 @default.
- W2414543630 countsByYear W24145436302021 @default.
- W2414543630 countsByYear W24145436302022 @default.
- W2414543630 crossrefType "journal-article" @default.
- W2414543630 hasAuthorship W2414543630A5017092378 @default.
- W2414543630 hasAuthorship W2414543630A5018987384 @default.
- W2414543630 hasAuthorship W2414543630A5091219809 @default.
- W2414543630 hasConcept C142724271 @default.
- W2414543630 hasConcept C203014093 @default.
- W2414543630 hasConcept C2775862500 @default.
- W2414543630 hasConcept C2778260677 @default.
- W2414543630 hasConcept C2778690821 @default.
- W2414543630 hasConcept C2779134260 @default.
- W2414543630 hasConcept C2780479503 @default.
- W2414543630 hasConcept C2780942790 @default.
- W2414543630 hasConcept C71924100 @default.
- W2414543630 hasConcept C86803240 @default.
- W2414543630 hasConcept C8891405 @default.
- W2414543630 hasConceptScore W2414543630C142724271 @default.
- W2414543630 hasConceptScore W2414543630C203014093 @default.
- W2414543630 hasConceptScore W2414543630C2775862500 @default.
- W2414543630 hasConceptScore W2414543630C2778260677 @default.
- W2414543630 hasConceptScore W2414543630C2778690821 @default.
- W2414543630 hasConceptScore W2414543630C2779134260 @default.
- W2414543630 hasConceptScore W2414543630C2780479503 @default.
- W2414543630 hasConceptScore W2414543630C2780942790 @default.
- W2414543630 hasConceptScore W2414543630C71924100 @default.
- W2414543630 hasConceptScore W2414543630C86803240 @default.
- W2414543630 hasConceptScore W2414543630C8891405 @default.
- W2414543630 hasIssue "60" @default.
- W2414543630 hasLocation W24145436301 @default.
- W2414543630 hasOpenAccess W2414543630 @default.
- W2414543630 hasPrimaryLocation W24145436301 @default.
- W2414543630 hasRelatedWork W1588520442 @default.
- W2414543630 hasRelatedWork W177209529 @default.
- W2414543630 hasRelatedWork W1982878668 @default.
- W2414543630 hasRelatedWork W1991081070 @default.
- W2414543630 hasRelatedWork W2018562824 @default.
- W2414543630 hasRelatedWork W2030912399 @default.
- W2414543630 hasRelatedWork W2034420655 @default.
- W2414543630 hasRelatedWork W2042013108 @default.
- W2414543630 hasRelatedWork W2083741917 @default.
- W2414543630 hasRelatedWork W2132227970 @default.
- W2414543630 hasRelatedWork W2212226399 @default.
- W2414543630 hasRelatedWork W2327304752 @default.
- W2414543630 hasRelatedWork W2418903962 @default.
- W2414543630 hasRelatedWork W2496248688 @default.
- W2414543630 hasRelatedWork W2804298954 @default.
- W2414543630 hasRelatedWork W3017785560 @default.
- W2414543630 hasRelatedWork W3029052526 @default.
- W2414543630 hasRelatedWork W3119478375 @default.
- W2414543630 hasRelatedWork W3170330284 @default.
- W2414543630 hasRelatedWork W46867079 @default.
- W2414543630 hasVolume "11" @default.
- W2414543630 isParatext "false" @default.
- W2414543630 isRetracted "false" @default.
- W2414543630 magId "2414543630" @default.
- W2414543630 workType "article" @default.