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- W2414679550 abstract "Bacground/Aim. Crohn's disease (CD) and ulcerative colitis (UC) are chronic, idiopathic, inflammatory diseases of the di- gestive tract. The aim of this study was to determine a possi- ble correlation between the clinical parameters of the disease activity degree and the presence of extraintestinal manifesta- tions with disease activity histopathological degree, in patients presented with CD and UC. Methods. This cross-sectional study included 134 patients (67 with CD and UC, respec- tively) treated at the Clinic of Gastroenterology, Clinical Center of Serbia, Belgrade. After clinical, laboratory, endo- scopic, histopathologic and radiologic diagnostics, the pa- tients were divided into two groups according to their histo- pathological activity. The group I comprised 79 patients whose values of five-grade histopathological activity were less than 5 (45 with CD and 34 with UC), while the group II con- sisted of 55 patients with the values higher than 5 (22 with CD and 33 with UC). The CD activity index (CDAI) and Truelove and Witts' scale of UC were used for clinical evaluation of the disease activity. Results. CD extraintestinal manifestations were present in 28.9% and 63.6% of the pa- tients in the groups I and II, respectively (p 0.05). Conclusion. In the patients presented with CD, the extraintestinal manifestations with higher CDAI suggested a higher degree of histopathological activity. On the contrary, in the UC patients, Truelove and Witts' scale and extraintesti- nal manifestations were not valid predictors of the disease histopathological activity." @default.
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- W2414679550 date "2013-01-01" @default.
- W2414679550 modified "2023-09-27" @default.
- W2414679550 title "Correlation between extraintestinal manifestations and clinical parameters with the histologic activity index in patients with inflammatory bowel diseases Povezanost vancrevnih manifestacija i klini˛ kih parametara sa indeksom histološke aktivnosti kod bolesnika sa inflamatornim bolestima creva" @default.
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