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- W2414719683 abstract "SUMMARY Salmeterol and formoterol are both β 2 ‐agonist bronchodilators with a long duration of action and are often classified together, yet they are distinctly different in their pharmacology. Recent evidence suggests there is a subpopulation of asthmatic patients who do not respond to salmeterol, yet can attain clinical benefit with formoterol. Following a literature search, three published case reports are reviewed as well as results from two published clinical trials designed specifically to document response to formoterol in ‘non‐responders to salmeterol’ asthmatics. Possible mechanisms underlying this observation are discussed, including pharmacological differences of the two drugs relating to agonism at the β2‐receptor and to effect on nuclear transcription factors." @default.
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- W2414719683 date "2001-09-01" @default.
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- W2414719683 title "CLINICAL EFFICACY WITH FORMOTEROL IN THE ABSENCE OF A RESPONSE TO SALMETEROL: A REVIEW" @default.
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- W2414719683 doi "https://doi.org/10.1111/j.1742-1241.2001.tb11094.x" @default.
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