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• W2414719940 abstract "The first report of blood-brain barrier (BBB) permeability by Paul Ehrlich (1) involved the use of the exogenous tracer Coerulean-S as described in Chapter 6 . Over the years, tracers of different sizes were introduced to study the permeability properties of normal cerebral vessels in physiologic and pathologic states (Table 1). Tracers provide information about the permeability status of vessels immediately before sacrifice. The disadvantage of exogenous tracers is that there are side effects associated with the administration of some tracers in live animals. The properties and methods by which some of these tracers are used to study BBB permeability to proteins and ions in pathologic states will be described." @default.
• W2414719940 created "2016-06-24" @default.
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• W2414719940 date "2003-11-14" @default.
• W2414719940 modified "2023-10-06" @default.
• W2414719940 title "Blood–Brain Barrier Permeability Using Tracers and Immunohistochemistry" @default.
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• W2414719940 doi "https://doi.org/10.1385/1-59259-419-0:133" @default.
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