Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414756803> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2414756803 endingPage "319" @default.
- W2414756803 startingPage "313" @default.
- W2414756803 abstract "The first step in the synthesis of all proteins in E. coli is the binding of N-formyl-methionine tRNA to a complex formed between a 30 S ribosome and a mRNA molecule (Nomura and Lowry, 1967). The N-formyl-methionine initiates the synthesis of the protein, becoming incorporated at the amino terminal end of the growing polypeptide chains (Capecchi, 1966). At some point in the synthesis of each protein either the formyl group or the formyl group and the methionine residue are cleaved off to expose the amino terminal residue of the finished protein. We made the assumption that the mechanism of chain initiation in mammalian cells would also result in the transient incorporation of an initiator molecule at the amino terminal position of the growing polypeptide chains. We decided to check on this assumption by studying the synthesis of the α chain of hemoglobin in rabbit reticulocytes. This system has two advantages:..." @default.
- W2414756803 created "2016-06-24" @default.
- W2414756803 creator A5017899142 @default.
- W2414756803 creator A5062376572 @default.
- W2414756803 date "1969-01-01" @default.
- W2414756803 modified "2023-09-26" @default.
- W2414756803 title "Initiation of the Chain of Rabbit Hemoglobin" @default.
- W2414756803 doi "https://doi.org/10.1101/sqb.1969.034.01.038" @default.
- W2414756803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5266169" @default.
- W2414756803 hasPublicationYear "1969" @default.
- W2414756803 type Work @default.
- W2414756803 sameAs 2414756803 @default.
- W2414756803 citedByCount "10" @default.
- W2414756803 countsByYear W24147568032015 @default.
- W2414756803 crossrefType "journal-article" @default.
- W2414756803 hasAuthorship W2414756803A5017899142 @default.
- W2414756803 hasAuthorship W2414756803A5062376572 @default.
- W2414756803 hasConcept C104317684 @default.
- W2414756803 hasConcept C153957851 @default.
- W2414756803 hasConcept C185592680 @default.
- W2414756803 hasConcept C2778321597 @default.
- W2414756803 hasConcept C2778917026 @default.
- W2414756803 hasConcept C2780912031 @default.
- W2414756803 hasConcept C2781338088 @default.
- W2414756803 hasConcept C2993989360 @default.
- W2414756803 hasConcept C3675279 @default.
- W2414756803 hasConcept C515207424 @default.
- W2414756803 hasConcept C55493867 @default.
- W2414756803 hasConcept C67705224 @default.
- W2414756803 hasConcept C71240020 @default.
- W2414756803 hasConcept C88478588 @default.
- W2414756803 hasConceptScore W2414756803C104317684 @default.
- W2414756803 hasConceptScore W2414756803C153957851 @default.
- W2414756803 hasConceptScore W2414756803C185592680 @default.
- W2414756803 hasConceptScore W2414756803C2778321597 @default.
- W2414756803 hasConceptScore W2414756803C2778917026 @default.
- W2414756803 hasConceptScore W2414756803C2780912031 @default.
- W2414756803 hasConceptScore W2414756803C2781338088 @default.
- W2414756803 hasConceptScore W2414756803C2993989360 @default.
- W2414756803 hasConceptScore W2414756803C3675279 @default.
- W2414756803 hasConceptScore W2414756803C515207424 @default.
- W2414756803 hasConceptScore W2414756803C55493867 @default.
- W2414756803 hasConceptScore W2414756803C67705224 @default.
- W2414756803 hasConceptScore W2414756803C71240020 @default.
- W2414756803 hasConceptScore W2414756803C88478588 @default.
- W2414756803 hasIssue "0" @default.
- W2414756803 hasLocation W24147568031 @default.
- W2414756803 hasLocation W24147568032 @default.
- W2414756803 hasOpenAccess W2414756803 @default.
- W2414756803 hasPrimaryLocation W24147568031 @default.
- W2414756803 hasRelatedWork W1987122174 @default.
- W2414756803 hasRelatedWork W2017838491 @default.
- W2414756803 hasRelatedWork W2049462770 @default.
- W2414756803 hasRelatedWork W2077729003 @default.
- W2414756803 hasRelatedWork W2133809618 @default.
- W2414756803 hasRelatedWork W2315418775 @default.
- W2414756803 hasRelatedWork W2442498676 @default.
- W2414756803 hasRelatedWork W2756459508 @default.
- W2414756803 hasRelatedWork W2803895723 @default.
- W2414756803 hasRelatedWork W2951926735 @default.
- W2414756803 hasVolume "34" @default.
- W2414756803 isParatext "false" @default.
- W2414756803 isRetracted "false" @default.
- W2414756803 magId "2414756803" @default.
- W2414756803 workType "article" @default.