Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414805212> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2414805212 endingPage "73" @default.
- W2414805212 startingPage "367" @default.
- W2414805212 abstract "In this study, rhenium sulfide colloidal nanoparticles were developed as radiopharmaceutical for sentinel lymph node detection. We directly used rhenium sulfide as a starting material for the preparation of colloidal nanoparticles. UV-visible spectrophotometry was used for characterization of in house developed colloidal particles. The size distribution of radioactive particles was studied by using membrane filtration method. The percentage of radiolabeled colloidal nanoparticles was determined by paper chromatography (PC). The study also includes in vitro stability, protein binding in human blood and bioevaluation in a rabbit model. The results indicate that 77.27 ± 3.26 % particles of size less than 20nm (suitable for lymphoscintigraphy) were radiolabeled. (99m)Tc labeled rhenium sulfide labeling efficacy with the radiometal is 98.5 ± 0.5%, which remains considerably stable beyond 5h at room temperature. Furthermore, it was observed that 70.2 ± 1.3% radiolabeled colloid complex showed binding with the blood protein. Bioevaluation results show the remarkable achievement of our radiopharmaceutical. The in house prepared (99m)Tc labeled rhenium sulfide colloidal nanoparticles reached the sentinel node within 15 min of post injection. These results indicate that (99m)Tc labeled rhenium sulfide colloid nanoparticles kit produced by a novel procedure seems of significant potential as a feasible candidate for further development to be used in clinical practice." @default.
- W2414805212 created "2016-06-24" @default.
- W2414805212 creator A5010438652 @default.
- W2414805212 creator A5044997750 @default.
- W2414805212 creator A5057861396 @default.
- W2414805212 creator A5064215199 @default.
- W2414805212 creator A5067849119 @default.
- W2414805212 creator A5072848376 @default.
- W2414805212 creator A5089007210 @default.
- W2414805212 date "2013-03-01" @default.
- W2414805212 modified "2023-09-23" @default.
- W2414805212 title "In house development of (99m)Tc-Rhenium sulfide colloidal nanoparticles for sentinel lymph node detection." @default.
- W2414805212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23455209" @default.
- W2414805212 hasPublicationYear "2013" @default.
- W2414805212 type Work @default.
- W2414805212 sameAs 2414805212 @default.
- W2414805212 citedByCount "1" @default.
- W2414805212 countsByYear W24148052122015 @default.
- W2414805212 crossrefType "journal-article" @default.
- W2414805212 hasAuthorship W2414805212A5010438652 @default.
- W2414805212 hasAuthorship W2414805212A5044997750 @default.
- W2414805212 hasAuthorship W2414805212A5057861396 @default.
- W2414805212 hasAuthorship W2414805212A5064215199 @default.
- W2414805212 hasAuthorship W2414805212A5067849119 @default.
- W2414805212 hasAuthorship W2414805212A5072848376 @default.
- W2414805212 hasAuthorship W2414805212A5089007210 @default.
- W2414805212 hasConcept C121608353 @default.
- W2414805212 hasConcept C126322002 @default.
- W2414805212 hasConcept C13965031 @default.
- W2414805212 hasConcept C155672457 @default.
- W2414805212 hasConcept C171250308 @default.
- W2414805212 hasConcept C177322064 @default.
- W2414805212 hasConcept C178790620 @default.
- W2414805212 hasConcept C179104552 @default.
- W2414805212 hasConcept C185592680 @default.
- W2414805212 hasConcept C192562407 @default.
- W2414805212 hasConcept C2780212769 @default.
- W2414805212 hasConcept C2780596425 @default.
- W2414805212 hasConcept C43617362 @default.
- W2414805212 hasConcept C505216180 @default.
- W2414805212 hasConcept C522557706 @default.
- W2414805212 hasConcept C530470458 @default.
- W2414805212 hasConcept C59789625 @default.
- W2414805212 hasConcept C71924100 @default.
- W2414805212 hasConceptScore W2414805212C121608353 @default.
- W2414805212 hasConceptScore W2414805212C126322002 @default.
- W2414805212 hasConceptScore W2414805212C13965031 @default.
- W2414805212 hasConceptScore W2414805212C155672457 @default.
- W2414805212 hasConceptScore W2414805212C171250308 @default.
- W2414805212 hasConceptScore W2414805212C177322064 @default.
- W2414805212 hasConceptScore W2414805212C178790620 @default.
- W2414805212 hasConceptScore W2414805212C179104552 @default.
- W2414805212 hasConceptScore W2414805212C185592680 @default.
- W2414805212 hasConceptScore W2414805212C192562407 @default.
- W2414805212 hasConceptScore W2414805212C2780212769 @default.
- W2414805212 hasConceptScore W2414805212C2780596425 @default.
- W2414805212 hasConceptScore W2414805212C43617362 @default.
- W2414805212 hasConceptScore W2414805212C505216180 @default.
- W2414805212 hasConceptScore W2414805212C522557706 @default.
- W2414805212 hasConceptScore W2414805212C530470458 @default.
- W2414805212 hasConceptScore W2414805212C59789625 @default.
- W2414805212 hasConceptScore W2414805212C71924100 @default.
- W2414805212 hasIssue "2" @default.
- W2414805212 hasLocation W24148052121 @default.
- W2414805212 hasOpenAccess W2414805212 @default.
- W2414805212 hasPrimaryLocation W24148052121 @default.
- W2414805212 hasRelatedWork W134778924 @default.
- W2414805212 hasRelatedWork W2039519499 @default.
- W2414805212 hasRelatedWork W2069951004 @default.
- W2414805212 hasRelatedWork W2077869839 @default.
- W2414805212 hasRelatedWork W2086398900 @default.
- W2414805212 hasRelatedWork W2414805212 @default.
- W2414805212 hasRelatedWork W2556471210 @default.
- W2414805212 hasRelatedWork W3008494875 @default.
- W2414805212 hasRelatedWork W3133705511 @default.
- W2414805212 hasRelatedWork W4234518087 @default.
- W2414805212 hasVolume "26" @default.
- W2414805212 isParatext "false" @default.
- W2414805212 isRetracted "false" @default.
- W2414805212 magId "2414805212" @default.
- W2414805212 workType "article" @default.