Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414831765> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2414831765 endingPage "8" @default.
- W2414831765 startingPage "3294" @default.
- W2414831765 abstract "Vemurafenib has shown significant activity in V600 mutant melanoma; however the role of this agent in Lung adenocarcinoma with an activating BRAF mutation is still evolving. One of our patients had a rare activating BRAF mutation detected through tumor exome sequencing, which led to a switch from her successful therapy to Vemurafenib and ultimately tumor progression. The lack of adequate response was disappointing both in terms of lost disease free survival and heavy financial burden to the patient who had to cover the charges of her unsuccessful off-label therapy. This experience, despite its highlight of treatment failure, puts into question the use of next generation sequencing and the trend for using off-label agents in pursuit of an optimal response without the support of strong clinical evidence." @default.
- W2414831765 created "2016-06-24" @default.
- W2414831765 creator A5005356941 @default.
- W2414831765 creator A5023103412 @default.
- W2414831765 creator A5040346287 @default.
- W2414831765 creator A5049746160 @default.
- W2414831765 creator A5058706934 @default.
- W2414831765 creator A5061289193 @default.
- W2414831765 creator A5081995311 @default.
- W2414831765 date "2015-01-01" @default.
- W2414831765 modified "2023-09-27" @default.
- W2414831765 title "BRAFV600 mutant non-small-cell lung cancer resistant to Vemurafenib." @default.
- W2414831765 cites W1981626262 @default.
- W2414831765 cites W2006938406 @default.
- W2414831765 cites W2014881369 @default.
- W2414831765 cites W2018802677 @default.
- W2414831765 cites W2064854706 @default.
- W2414831765 cites W2092998235 @default.
- W2414831765 cites W2096024381 @default.
- W2414831765 cites W2111580893 @default.
- W2414831765 cites W2127919472 @default.
- W2414831765 cites W2149411742 @default.
- W2414831765 cites W2151281047 @default.
- W2414831765 cites W2160304102 @default.
- W2414831765 cites W2163188200 @default.
- W2414831765 cites W2171139285 @default.
- W2414831765 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4440164" @default.
- W2414831765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26045855" @default.
- W2414831765 hasPublicationYear "2015" @default.
- W2414831765 type Work @default.
- W2414831765 sameAs 2414831765 @default.
- W2414831765 citedByCount "2" @default.
- W2414831765 countsByYear W24148317652015 @default.
- W2414831765 countsByYear W24148317652016 @default.
- W2414831765 crossrefType "journal-article" @default.
- W2414831765 hasAuthorship W2414831765A5005356941 @default.
- W2414831765 hasAuthorship W2414831765A5023103412 @default.
- W2414831765 hasAuthorship W2414831765A5040346287 @default.
- W2414831765 hasAuthorship W2414831765A5049746160 @default.
- W2414831765 hasAuthorship W2414831765A5058706934 @default.
- W2414831765 hasAuthorship W2414831765A5061289193 @default.
- W2414831765 hasAuthorship W2414831765A5081995311 @default.
- W2414831765 hasConcept C104317684 @default.
- W2414831765 hasConcept C121608353 @default.
- W2414831765 hasConcept C126322002 @default.
- W2414831765 hasConcept C143065580 @default.
- W2414831765 hasConcept C143998085 @default.
- W2414831765 hasConcept C16671776 @default.
- W2414831765 hasConcept C2776131300 @default.
- W2414831765 hasConcept C2776256026 @default.
- W2414831765 hasConcept C2777658100 @default.
- W2414831765 hasConcept C2781182431 @default.
- W2414831765 hasConcept C2781230642 @default.
- W2414831765 hasConcept C2994587330 @default.
- W2414831765 hasConcept C501734568 @default.
- W2414831765 hasConcept C502942594 @default.
- W2414831765 hasConcept C54355233 @default.
- W2414831765 hasConcept C60644358 @default.
- W2414831765 hasConcept C71924100 @default.
- W2414831765 hasConcept C86803240 @default.
- W2414831765 hasConceptScore W2414831765C104317684 @default.
- W2414831765 hasConceptScore W2414831765C121608353 @default.
- W2414831765 hasConceptScore W2414831765C126322002 @default.
- W2414831765 hasConceptScore W2414831765C143065580 @default.
- W2414831765 hasConceptScore W2414831765C143998085 @default.
- W2414831765 hasConceptScore W2414831765C16671776 @default.
- W2414831765 hasConceptScore W2414831765C2776131300 @default.
- W2414831765 hasConceptScore W2414831765C2776256026 @default.
- W2414831765 hasConceptScore W2414831765C2777658100 @default.
- W2414831765 hasConceptScore W2414831765C2781182431 @default.
- W2414831765 hasConceptScore W2414831765C2781230642 @default.
- W2414831765 hasConceptScore W2414831765C2994587330 @default.
- W2414831765 hasConceptScore W2414831765C501734568 @default.
- W2414831765 hasConceptScore W2414831765C502942594 @default.
- W2414831765 hasConceptScore W2414831765C54355233 @default.
- W2414831765 hasConceptScore W2414831765C60644358 @default.
- W2414831765 hasConceptScore W2414831765C71924100 @default.
- W2414831765 hasConceptScore W2414831765C86803240 @default.
- W2414831765 hasIssue "3" @default.
- W2414831765 hasLocation W24148317651 @default.
- W2414831765 hasOpenAccess W2414831765 @default.
- W2414831765 hasPrimaryLocation W24148317651 @default.
- W2414831765 hasRelatedWork W1510276410 @default.
- W2414831765 hasRelatedWork W1875726064 @default.
- W2414831765 hasRelatedWork W1921841920 @default.
- W2414831765 hasRelatedWork W2005549978 @default.
- W2414831765 hasRelatedWork W2029761866 @default.
- W2414831765 hasRelatedWork W2617846385 @default.
- W2414831765 hasRelatedWork W2808608845 @default.
- W2414831765 hasRelatedWork W2991122722 @default.
- W2414831765 hasRelatedWork W3023401146 @default.
- W2414831765 hasRelatedWork W3171615116 @default.
- W2414831765 hasVolume "8" @default.
- W2414831765 isParatext "false" @default.
- W2414831765 isRetracted "false" @default.
- W2414831765 magId "2414831765" @default.
- W2414831765 workType "article" @default.