Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414865802> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2414865802 endingPage "351" @default.
- W2414865802 startingPage "351" @default.
- W2414865802 abstract "Candidemia is becoming more actual because of better survival of even critically ill patients, wide use of antimicrobials, and increased numbers of invasive procedures and manipulations. Diagnosis of candidemia remains complicated, and costs of treatment and mortality rates are increasing. Objective. To evaluate the pathogens of candidemia, risk factors and their influence on outcome. Material and methods. Data of 41 patients with positive blood culture for Candida spp., who were treated in the intensive care units at the Hospital of Kaunas University of Medicine, were analyzed retrospectively. Results. Candidemia was caused by Candida albicans (C. albicans) in 48.8% (n=20) of patients and by non-albicans Candida in 51.2% (n=21) of patients. The main cause of candidemia was C. albicans in 2004 (83.3%, n=5), but in 2005 (63.6%, n=7), in 2006 (57.1%, n=4), and in 2007 (52.9%, n=9), the main cause was non-albicans Candida spp. The number of candidemia cases caused by C. albicans was decreased in 2005, 2006, and 2007 as compared with 2004, and the number of candidemia caused by non-albicans Candida spp. was decreased, respectively (P<0.05). More than 65% (n=34) of patients had severe disease (P<0.05). Lethal outcome was recorded in 58.5% of patients with candidemia. Mechanical ventilation was used in 76.9% (n=20) and urinary bladder catheter in 72.1% (n=19) of non-survivors and in 23.1% (n=6) and 26.9% (n=7) of survivors, respectively (P<0.05). Conclusions. There is an increase in the prevalence of candidemia in the intensive care units during the 4-year period; half of candidemia cases were caused by non-albicans Candida spp., and patients with candidemia caused by non-albicans Candida spp. are at higher risk of mortality. Therefore, for the empirical treatment of septic conditions in an intensive care unit, when invasive fungal infection is suspected, we recommend using an antifungal agent of non-azole class until a pathogen of candidemia is determined. Severe disease is evaluated as a risk factor for candidemia. Patients with oncological diseases are at significantly higher risk for candidemia caused by non-albicans Candida spp. Use of mechanical ventilation and urinary bladder catheter is a risk factor for lethal outcome." @default.
- W2414865802 created "2016-06-24" @default.
- W2414865802 creator A5027402076 @default.
- W2414865802 creator A5052155719 @default.
- W2414865802 creator A5078692784 @default.
- W2414865802 creator A5079234577 @default.
- W2414865802 date "2008-10-26" @default.
- W2414865802 modified "2023-09-25" @default.
- W2414865802 title "Candidemia in an intensive care unit" @default.
- W2414865802 doi "https://doi.org/10.3390/medicina45050044" @default.
- W2414865802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19535880" @default.
- W2414865802 hasPublicationYear "2008" @default.
- W2414865802 type Work @default.
- W2414865802 sameAs 2414865802 @default.
- W2414865802 citedByCount "2" @default.
- W2414865802 countsByYear W24148658022021 @default.
- W2414865802 countsByYear W24148658022022 @default.
- W2414865802 crossrefType "journal-article" @default.
- W2414865802 hasAuthorship W2414865802A5027402076 @default.
- W2414865802 hasAuthorship W2414865802A5052155719 @default.
- W2414865802 hasAuthorship W2414865802A5078692784 @default.
- W2414865802 hasAuthorship W2414865802A5079234577 @default.
- W2414865802 hasBestOaLocation W24148658021 @default.
- W2414865802 hasConcept C126322002 @default.
- W2414865802 hasConcept C141071460 @default.
- W2414865802 hasConcept C145081991 @default.
- W2414865802 hasConcept C177713679 @default.
- W2414865802 hasConcept C2776376669 @default.
- W2414865802 hasConcept C2777080012 @default.
- W2414865802 hasConcept C2780558435 @default.
- W2414865802 hasConcept C2780908437 @default.
- W2414865802 hasConcept C2780917455 @default.
- W2414865802 hasConcept C2987404301 @default.
- W2414865802 hasConcept C71924100 @default.
- W2414865802 hasConcept C86803240 @default.
- W2414865802 hasConcept C89423630 @default.
- W2414865802 hasConceptScore W2414865802C126322002 @default.
- W2414865802 hasConceptScore W2414865802C141071460 @default.
- W2414865802 hasConceptScore W2414865802C145081991 @default.
- W2414865802 hasConceptScore W2414865802C177713679 @default.
- W2414865802 hasConceptScore W2414865802C2776376669 @default.
- W2414865802 hasConceptScore W2414865802C2777080012 @default.
- W2414865802 hasConceptScore W2414865802C2780558435 @default.
- W2414865802 hasConceptScore W2414865802C2780908437 @default.
- W2414865802 hasConceptScore W2414865802C2780917455 @default.
- W2414865802 hasConceptScore W2414865802C2987404301 @default.
- W2414865802 hasConceptScore W2414865802C71924100 @default.
- W2414865802 hasConceptScore W2414865802C86803240 @default.
- W2414865802 hasConceptScore W2414865802C89423630 @default.
- W2414865802 hasIssue "5" @default.
- W2414865802 hasLocation W24148658021 @default.
- W2414865802 hasLocation W24148658022 @default.
- W2414865802 hasOpenAccess W2414865802 @default.
- W2414865802 hasPrimaryLocation W24148658021 @default.
- W2414865802 hasRelatedWork W2024910988 @default.
- W2414865802 hasRelatedWork W2076836450 @default.
- W2414865802 hasRelatedWork W2095442170 @default.
- W2414865802 hasRelatedWork W2102861863 @default.
- W2414865802 hasRelatedWork W2111989350 @default.
- W2414865802 hasRelatedWork W2146129413 @default.
- W2414865802 hasRelatedWork W2186844980 @default.
- W2414865802 hasRelatedWork W2273653842 @default.
- W2414865802 hasRelatedWork W2353492387 @default.
- W2414865802 hasRelatedWork W2946449973 @default.
- W2414865802 hasVolume "45" @default.
- W2414865802 isParatext "false" @default.
- W2414865802 isRetracted "false" @default.
- W2414865802 magId "2414865802" @default.
- W2414865802 workType "article" @default.