FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2414876934> ?p ?o ?g. }

• W2414876934 endingPage "E493" @default.
• W2414876934 startingPage "E487" @default.
• W2414876934 abstract "We determined the effect of insulin on the fate of glucose and contractile function in isolated working hypertrophied hearts from rats with an aortic constriction ( n = 27) and control hearts from sham-operated rats ( n = 27). Insulin increased glycolysis and glycogen in control and hypertrophied hearts. The change in glycogen was brought about by increased glycogen synthesis and decreased glycogenolysis in both groups. However, the magnitude of change in glycolysis, glycogen synthesis, and glycogenolysis caused by insulin was lower in hypertrophied hearts than in control hearts. Insulin also increased glucose oxidation and contractile function in control hearts but not in hypertrophied hearts. Protein content of glucose transporters, protein kinase B, and phosphatidylinositol 3-kinase was not different between the two groups. Thus hypertrophied hearts are less responsive to the metabolic and functional effects of insulin. The reduced responsiveness involves multiple aspects of glucose metabolism, including glycolysis, glucose oxidation, and glycogen metabolism. The absence of changes in content of key regulatory molecules indicates that other sites, pathways, or factors regulating glucose utilization are responsible for these findings." @default.
• W2414876934 created "2016-06-24" @default.
• W2414876934 creator A5003110659 @default.
• W2414876934 creator A5008981001 @default.
• W2414876934 creator A5012360155 @default.
• W2414876934 creator A5020770877 @default.
• W2414876934 creator A5029854238 @default.
• W2414876934 creator A5031996352 @default.
• W2414876934 creator A5064876009 @default.
• W2414876934 creator A5070573850 @default.
• W2414876934 creator A5074110521 @default.
• W2414876934 creator A5074174757 @default.
• W2414876934 date "2000-09-01" @default.
• W2414876934 modified "2023-10-15" @default.
• W2414876934 title "Hypertrophied rat hearts are less responsive to the metabolic and functional effects of insulin" @default.
• W2414876934 cites W1031730619 @default.
• W2414876934 cites W1488748351 @default.
• W2414876934 cites W1636709211 @default.
• W2414876934 cites W1781422850 @default.
• W2414876934 cites W1948436988 @default.
• W2414876934 cites W197348414 @default.
• W2414876934 cites W1983450443 @default.
• W2414876934 cites W1984513597 @default.
• W2414876934 cites W1985754874 @default.
• W2414876934 cites W1985802637 @default.
• W2414876934 cites W1987578547 @default.
• W2414876934 cites W1994889584 @default.
• W2414876934 cites W1998722759 @default.
• W2414876934 cites W2011395193 @default.
• W2414876934 cites W2017903413 @default.
• W2414876934 cites W2021321498 @default.
• W2414876934 cites W2029651486 @default.
• W2414876934 cites W2031141693 @default.
• W2414876934 cites W2036637373 @default.
• W2414876934 cites W2045405791 @default.
• W2414876934 cites W2053718938 @default.
• W2414876934 cites W2061088776 @default.
• W2414876934 cites W2071323212 @default.
• W2414876934 cites W2097276354 @default.
• W2414876934 cites W2117814288 @default.
• W2414876934 cites W2124009251 @default.
• W2414876934 cites W2133916361 @default.
• W2414876934 cites W2152013966 @default.
• W2414876934 cites W2217333788 @default.
• W2414876934 cites W2341112758 @default.
• W2414876934 cites W2394826799 @default.
• W2414876934 cites W2399792411 @default.
• W2414876934 cites W4234406986 @default.
• W2414876934 doi "https://doi.org/10.1152/ajpendo.2000.279.3.e487" @default.
• W2414876934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10950814" @default.
• W2414876934 hasPublicationYear "2000" @default.
• W2414876934 type Work @default.
• W2414876934 sameAs 2414876934 @default.
• W2414876934 citedByCount "45" @default.
• W2414876934 countsByYear W24148769342012 @default.
• W2414876934 countsByYear W24148769342013 @default.
• W2414876934 countsByYear W24148769342014 @default.
• W2414876934 countsByYear W24148769342015 @default.
• W2414876934 countsByYear W24148769342016 @default.
• W2414876934 countsByYear W24148769342017 @default.
• W2414876934 countsByYear W24148769342020 @default.
• W2414876934 crossrefType "journal-article" @default.
• W2414876934 hasAuthorship W2414876934A5003110659 @default.
• W2414876934 hasAuthorship W2414876934A5008981001 @default.
• W2414876934 hasAuthorship W2414876934A5012360155 @default.
• W2414876934 hasAuthorship W2414876934A5020770877 @default.
• W2414876934 hasAuthorship W2414876934A5029854238 @default.
• W2414876934 hasAuthorship W2414876934A5031996352 @default.
• W2414876934 hasAuthorship W2414876934A5064876009 @default.
• W2414876934 hasAuthorship W2414876934A5070573850 @default.
• W2414876934 hasAuthorship W2414876934A5074110521 @default.
• W2414876934 hasAuthorship W2414876934A5074174757 @default.
• W2414876934 hasConcept C126322002 @default.
• W2414876934 hasConcept C134018914 @default.
• W2414876934 hasConcept C161573976 @default.
• W2414876934 hasConcept C17093226 @default.
• W2414876934 hasConcept C184235292 @default.
• W2414876934 hasConcept C185592680 @default.
• W2414876934 hasConcept C192118531 @default.
• W2414876934 hasConcept C20251656 @default.
• W2414876934 hasConcept C2777499176 @default.
• W2414876934 hasConcept C2777866211 @default.
• W2414876934 hasConcept C2777949327 @default.
• W2414876934 hasConcept C2779306644 @default.
• W2414876934 hasConcept C2780610907 @default.
• W2414876934 hasConcept C55493867 @default.
• W2414876934 hasConcept C62231903 @default.
• W2414876934 hasConcept C71924100 @default.
• W2414876934 hasConcept C86803240 @default.
• W2414876934 hasConceptScore W2414876934C126322002 @default.
• W2414876934 hasConceptScore W2414876934C134018914 @default.
• W2414876934 hasConceptScore W2414876934C161573976 @default.
• W2414876934 hasConceptScore W2414876934C17093226 @default.
• W2414876934 hasConceptScore W2414876934C184235292 @default.
• W2414876934 hasConceptScore W2414876934C185592680 @default.
• W2414876934 hasConceptScore W2414876934C192118531 @default.
• W2414876934 hasConceptScore W2414876934C20251656 @default.
• W2414876934 hasConceptScore W2414876934C2777499176 @default.

• next