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• W2414972006 abstract "Primary biliary cholangitis is a chronic, cholestatic liver disease characterized by a heterogeneous presentation, symptomatology, disease progression and response to therapy. In contrast, clinical management and treatment of PBC is homogeneous with a ‘one size fits all’ approach. The evolving research landscape, with the emergence of the -omics field and the availability of large patient cohorts are creating a unique opportunity of translational epidemiology. Furthermore, several novel disease and symptom-modifying agents for PBC are currently in development. The time is therefore ripe for precision medicine in PBC. In this manuscript we describe the concept of precision medicine; review current approaches to risk-stratification in PBC, and speculate how precision medicine in PBC might develop in the near future." @default.
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• W2414972006 date "2016-08-01" @default.
• W2414972006 modified "2023-10-17" @default.
• W2414972006 title "Toward precision medicine in primary biliary cholangitis" @default.
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• W2414972006 doi "https://doi.org/10.1016/j.dld.2016.05.023" @default.
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