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- W2414993944 abstract "Background/Aims: There are few reports about the cholinergic regulation of gastric electrical activities using percutaneous electrogastrograms (EGG). To determine the effect of intravenous administration of a vagal blocker (atropine sulfate) or a vagal stimulator (neostigmine) on gastric electrical activities EGG was utilized in this study. Methodology: EGG was recorded before and after administration of a vagal blocker (atropine sulfate, 0.02mg/kg) and/or vagal stimulator (neostigmine, 0.008mg/kg) in six normal volunteers. Results: After administration of atropine sulfate, the original waves on EGG almost disappeared and decreased amplitudes were detected by visual inspection in all subjects. Moreover, increase amplitude on EGG was clearly demonstrated after administration of neostigmine in all subjects. It was also shown that the effects of these medicines persisted more than 60 minutes after injection. Conclusions: These findings suggest that the EGG reflected gastric motility, and that neurological regulation of EGG was mediated through the vagal and/or cholinergic efferent pathway." @default.
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- W2414993944 date "2008-01-01" @default.
- W2414993944 modified "2023-09-28" @default.
- W2414993944 title "Effects of atropine sulfate and neostigmine on gastric electrical activity in human subjects--electrogastrographic study." @default.
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