FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2415149682> ?p ?o ?g. }

• W2415149682 endingPage "231" @default.
• W2415149682 startingPage "218" @default.
• W2415149682 abstract "Growth of solid tumors beyond a certain mass is dependent on the vascular bed from pre-existing host vasculature. The process of angiogenesis is essential not only for primary tumor growth but also for metastasis. The number of microvessels within the invasive component of a primary tumor reflects the degree of tumor angiogenesis. At present the most widely used method to assess neovascularization is the quantitation of intratumoral microvessel density (IMD) by immunohistochemical methods in which specific markers for endothelial cells are employed. In this paper we analyze the different methods used to assess IMD, as well as their advantages and potential methodological pitfalls. Several studies have shown a close correlation between IMD, tumor growth and the occurrence of metastasis, suggesting that IMD is a prognostic indicator of clinical relevance. Furthermore, preliminary studies suggest that determination of angiogenesis may predict responsiveness to some forms of conventional anticancer therapy. Although the histological microvessel density technique is the current gold standard to characterize tumor angiogenesis, it may not be the ideal tool for clinical purposes because it needs to be performed on biopsy material and does not assess the functional pathways involved in the angiogenic activity of tumors. Non-invasive assessment of tumor vascularity is possible in vivo by means of Doppler sonography, dynamic contrast-enhanced magnetic resonance imaging (MRI) and positron emission tomography (PET). These methods may be preferable to histological assay because they are non-invasive, survey the entire tumor, reflect both anatomic and physiologic characteristics, and may be useful to monitor the activity of antiangiogenic therapies." @default.
• W2415149682 created "2016-06-24" @default.
• W2415149682 creator A5001899541 @default.
• W2415149682 creator A5005328693 @default.
• W2415149682 creator A5025938497 @default.
• W2415149682 creator A5058172205 @default.
• W2415149682 date "1999-10-01" @default.
• W2415149682 modified "2023-10-12" @default.
• W2415149682 title "Assessment of Tumor Vascularization: Immunohistochemical and Non-Invasive Methods" @default.
• W2415149682 cites W120565579 @default.
• W2415149682 cites W142558519 @default.
• W2415149682 cites W1837651204 @default.
• W2415149682 cites W1899169161 @default.
• W2415149682 cites W1973651359 @default.
• W2415149682 cites W1973893754 @default.
• W2415149682 cites W1975104031 @default.
• W2415149682 cites W1976195989 @default.
• W2415149682 cites W1976295600 @default.
• W2415149682 cites W1976497875 @default.
• W2415149682 cites W1978139448 @default.
• W2415149682 cites W1980878140 @default.
• W2415149682 cites W1984758613 @default.
• W2415149682 cites W1985248941 @default.
• W2415149682 cites W1988978946 @default.
• W2415149682 cites W1990036692 @default.
• W2415149682 cites W1993593600 @default.
• W2415149682 cites W1997309644 @default.
• W2415149682 cites W1997852033 @default.
• W2415149682 cites W1998316947 @default.
• W2415149682 cites W2003032376 @default.
• W2415149682 cites W2007239042 @default.
• W2415149682 cites W2008920831 @default.
• W2415149682 cites W2014511585 @default.
• W2415149682 cites W2016859917 @default.
• W2415149682 cites W2020925369 @default.
• W2415149682 cites W2024952109 @default.
• W2415149682 cites W2027192494 @default.
• W2415149682 cites W2029773366 @default.
• W2415149682 cites W2029877619 @default.
• W2415149682 cites W2033791403 @default.
• W2415149682 cites W2036006576 @default.
• W2415149682 cites W2037761545 @default.
• W2415149682 cites W2040328047 @default.
• W2415149682 cites W2040643478 @default.
• W2415149682 cites W2047112531 @default.
• W2415149682 cites W2047187896 @default.
• W2415149682 cites W2050740674 @default.
• W2415149682 cites W2051526950 @default.
• W2415149682 cites W2052626837 @default.
• W2415149682 cites W2054294404 @default.
• W2415149682 cites W2055394964 @default.
• W2415149682 cites W2063796305 @default.
• W2415149682 cites W2064297621 @default.
• W2415149682 cites W2066641104 @default.
• W2415149682 cites W2068547096 @default.
• W2415149682 cites W2071328106 @default.
• W2415149682 cites W2071389244 @default.
• W2415149682 cites W2074070420 @default.
• W2415149682 cites W2079878526 @default.
• W2415149682 cites W2083186952 @default.
• W2415149682 cites W2092644885 @default.
• W2415149682 cites W2093096127 @default.
• W2415149682 cites W2101514446 @default.
• W2415149682 cites W2105986437 @default.
• W2415149682 cites W2113257521 @default.
• W2415149682 cites W2129299792 @default.
• W2415149682 cites W2133037916 @default.
• W2415149682 cites W2139933832 @default.
• W2415149682 cites W2147282867 @default.
• W2415149682 cites W2151967532 @default.
• W2415149682 cites W2154724295 @default.
• W2415149682 cites W2158743409 @default.
• W2415149682 cites W2319962899 @default.
• W2415149682 cites W2327978182 @default.
• W2415149682 cites W2412558194 @default.
• W2415149682 cites W4236665940 @default.
• W2415149682 cites W4245635197 @default.
• W2415149682 cites W4318470538 @default.
• W2415149682 cites W87202805 @default.
• W2415149682 doi "https://doi.org/10.1177/172460089901400405" @default.
• W2415149682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10669950" @default.
• W2415149682 hasPublicationYear "1999" @default.
• W2415149682 type Work @default.
• W2415149682 sameAs 2415149682 @default.
• W2415149682 citedByCount "41" @default.
• W2415149682 countsByYear W24151496822013 @default.
• W2415149682 countsByYear W24151496822015 @default.
• W2415149682 countsByYear W24151496822016 @default.
• W2415149682 countsByYear W24151496822017 @default.
• W2415149682 countsByYear W24151496822019 @default.
• W2415149682 countsByYear W24151496822020 @default.
• W2415149682 countsByYear W24151496822023 @default.
• W2415149682 crossrefType "journal-article" @default.
• W2415149682 hasAuthorship W2415149682A5001899541 @default.
• W2415149682 hasAuthorship W2415149682A5005328693 @default.
• W2415149682 hasAuthorship W2415149682A5025938497 @default.
• W2415149682 hasAuthorship W2415149682A5058172205 @default.
• W2415149682 hasBestOaLocation W24151496821 @default.

• next