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- W2415202961 abstract "Asthma is a chronic inflammatory airways disease. The inflammatory process is in many patients driven by an immunoglobulin E (IgE)-dependent process. Patients with severe asthma are at high risk of serious exacerbations and death and have few therapeutic options available. Omalizumab is a humanized monoclonal antibody that acts by binding to and inhibiting the effects of IgE, thereby interfering with one aspect of the asthma cascade. In addition to decreasing exacerbations, it has a steroid sparing role and many beneficial effects in asthma. As suggested by the new asthma GINA 2006 guidelines, this biological agent is indicated in severe persistent allergic asthma." @default.
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- W2415202961 date "2009-05-01" @default.
- W2415202961 modified "2023-09-23" @default.
- W2415202961 title "Omralizumab (Xolair) in severe persistent allergic asthma" @default.
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