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- W2415206593 abstract "Gamma-interferon appears to be a pivotal molecule in the immune system. Recombinant DNA technology has permitted the cloning and expression of the gene for gamma-interferon (gamma-IFN), leading to an exponential increase in the level of knowledge both in vitro and in vivo. Laboratory evidence suggests a clinical role for gamma-IFN in collagen vascular disease, chronic granulomatous infectious diseases, hematology, and medical oncology. Phase I trials have identified the toxicities; these toxicities are primarily clinical and include fever, fatigue, flu-like symptoms, and hypotension. Antitumor activity has been noted in the early development of the drug." @default.
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- W2415206593 date "1987-06-01" @default.
- W2415206593 modified "2023-09-23" @default.
- W2415206593 title "Gamma-interferon: physiology and speculation on its role in medicine." @default.
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